Eagles vs Buccaneers Odds, Pick, Prediction | Monday Night Football

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Getty Images. Pictured: Jalen Hurts (left) and Baker Mayfield (right).

Eagles vs Buccaneers Odds

Monday, Sept. 25
7:15 p.m. ET
ABC | ESPN+
Eagles Odds
SpreadTotalMoneyline
-5.5
-115
44
-110o / -110u
-245
Buccaneers Odds
SpreadTotalMoneyline
+5.5
-105
44
-110o / -110u
+205
Odds via bet365. Get up-to-the-minute NFL odds here.

Eagles vs Buccaneers odds have the reigning NFC champions favored in the first of two Monday Night Football games in Week 3.

The winner of this game between Philadelphia and Tampa Bay will join the 49ers as the last undefeated teams standing in the NFC – only Miami holds that distinction in the AFC. Can Tampa Bay make it three straight to start the season for the first time since 2005, or will the defending NFC Champs continue their conference dominance?

Let's break down the matchup and make our Eagles vs. Buccaneers picks on the spread and total.


Eagles vs. Buccaneers

Matchup Analysis

Baker Mayfield has played well this season, leading a Bucs offense that has yet to turn the ball over, which is something no other NFC team can say.

However, he's faced Minnesota and Chicago — two winless teams that have two of the worst defenses in the league. Neither of those units can generate pressure without the blitz, or match up on the back end because of weak secondaries.

That's not the case with the Eagles — they boast one of the top defensive lines and should win the battle up front against a vulnerable Tampa Bay offensive line. Philly also has a pair of capable corners on the outside with Darius Slay and James Bradberry, the latter of which is returning from injury.

That spells bad news for Mayfield, who has struggled immensely throughout his career against defenses that can generate pressure without bringing extra rushers. Contrary to popular opinion, Mayfield has actually fared OK against the blitz, with a higher touchdown-to-interception ratio against the blitz than against non-blitz packages.

Simply put, Mayfield has usually flopped against the type of defense the Eagles field.


Bet Eagles vs. Bucs at FanDuel

Eagles -5.5

Buccaneers +5.5


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While the Bucs have triumphed over two winless teams, the Eagles have defeated two teams with one combined victory in the Vikings and Patriots, who beat Zach Wilson for their only win — does that even count? Philly hasn't looked crisp during its unblemished start, holding on for dear life in Foxboro and benefiting from extreme turnover luck against Minnesota.

Entering the season, there were questions about the Eagles, specifically up the middle of the defense as well as staff turnover with two new coordinators. The jury is still out on the defense, which has dealt with injuries, but we know they have a pair of reliable corners and a defensive line that can get into opposing backfields.

I'm more worried about the offense, which has looked completely lost at times against defenses that have adjusted to the Jalen Hurts read-option offense by focusing on taking away the edge.

I also believe the play-calling has gotten much worse with a downgrade at offensive coordinator (Brian Johnson) — although I could be proven wrong given it's a sample size of just two games. For now, it looks like a problem to me. Philly ranks 30th in the NFL in drop-back success rate, in front of only the Jets and Titans.

Last week against Minnesota, Philly made an easy adjustment by just running it right at a bad defense. That won't be as easy against Tampa, which has almost always had a stingy run defense under Todd Bowles by design.

The Bucs have some injuries on that side of the ball worth monitoring, but until I see more rhythm, flow and adjustments from Philadelphia's offense, I'm assuming it will be a bit wonky and inefficient.

Eagles vs. Buccaneers

Betting Picks & Predictions

As I mentioned previously, this isn't an ideal matchup for Baker Mayfield.

However, I also think there are far too many issues with the current state of the Eagles offense. They've yet to show how they will counter the league's adjustments after Jalen Hurts exploded last season.

I trust the Tampa defense to have a fairly sound game plan; Philly won't be able to simply hand it off all night with the same level of success it enjoyed against Minnesota.

To me, the Bucs (at +4.5 or better) and the under (at 45 or higher) are both worth considering in what I think profiles as a low-scoring game based on the matchup. The home pup and the points are intriguing as I thought people were too low on the Buccaneers post-Tom Brady. People have seemingly forgotten that Tampa Bay has a decent roster overall.

Pick 1: Bucs +5.5 (Bet to +4.5)
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