Giants vs Bills Best Bets: Spread, Player Props | Sunday Night Football Picks
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Giants vs Bills Odds | Sunday Night Football
| Giants Odds | ||
|---|---|---|
| Spread | Over/Under | Moneyline |
+15.5 -110 | 43 -110o / -110u | +800 |
| Bills Odds | ||
|---|---|---|
| Spread | Over/Under | Moneyline |
-15.5 -110 | 43 -110o / -110u | -1300 |
Giants vs. Bills will conclude the Sunday NFL slate with a Sunday Night Football game at Highmark Stadium, and we have picks against the spread and player props.
To say the line for this intrastate rivalry game is one-sided would be an understatement. The Bills have settled as 15.5-point favorites on the spread with the Giants playing without Daniel Jones and turning to backup quarterback Tyrod Taylor. The over/under can be found at 43 or 43.5 points.
We have one betting analyst who is rather bold, as he favors the Giants against the spread (ATS) and even a sprinkle on the New York moneyline at +830. As for the player prop, it’s a bet on former Patriot Damien Harris to go over his rushing yards total.
Continue reading for our Giants vs. Bills best bets, plus our additional wall-to-wall Sunday Night Football coverage that includes more prop picks, a +433 same game parlay and more.
Giants vs. Bills Best Bets | Player Props, Spread Picks
The team logos in the table below represent each of the matchups that our NFL betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Game | Time (ET) | Pick |
|---|---|---|
| 8:20 p.m. | ||
| 8:20 p.m. | ||
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our NFL Odds page, which automatically surfaces the best lines for every game. | ||
Giants vs. Bills
There's no football case to be made for this awful Giants squad, but just like in poker, we gotta play the man, not the cards. The number and the spot tell us to bet New York. Some of my favorite trends:
- Underdogs that have scored 16 or less in three straight: 66% ATS
- Underdogs with an average margin of victory at -14 or worse Week 5 forward: 66% ATS
- Teams at 20% ATS or worse against opponents at 60% ATS or better after September: 62% ATS
- Teams on an L5 ATS streak (58% ATS) that are more than 11-point underdogs: 13-2 ATS (87%)
On top of all that are the post-London trends warning bettors off of Buffalo. Teams returning from overseas without a bye have been tied or trailing at some point in the fourth quarter of all such 11 games in NFL history. It's absolutely disgusting, but there's value on the Giants at this number.
And any moneyline this long is an auto bet. Since 2018, moneyline dogs at +750 or longer are 4-17 SU — so we're probably going to lose! — but have returned an incredible 76.9% ROI. Brian Daboll is 6-9-1 SU as an underdog, and this is his old team so he may have something to prove. I'll give him a chance.
Giants vs. Bills
By Matt Trebby
Harris has cleared this number twice this season, but the situation Buffalo finds itself in may lend itself to him showing value on his over.
The 26-year-old RB cleared this rushing total against the Raiders and Dolphins, against whom Buffalo controlled the game and won comfortably. As 15.5-point favorites on Sunday night, this could be another good spot for him to thrive.
Harris is averaging 4.2 yards per attempt this season with Buffalo. That means four carries put him right at this total, and he got at least six in those two aforementioned games.
In case my analysis wasn’t enough, Sean Koerner is projecting Harris for 25 rushing yards on Sunday Night Football.
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