Betting on quarterback ineptitude is one of my NFL guilty pleasures. I especially like back-breaking interceptions that completely flip the momentum of the game.
That’s why I’m diving headfirst into the quarterback interception market to identify key spots each week to cash in on quarterback miscues.
It’s worth noting that I track all interception props from each quarterback (Yes and No), and it’s been a huge windfall for bettors who choose to only bet on “YES” when they are plus-money (+100 or higher). In 2023, had you bet on every quarterback that was plus-money to throw an interception, you would’ve gone 87-91 for +17.2U. This was after it went 81-75 for +25.5U in 2022.
In 2025, we’re seeing far fewer quarterbacks with plus-odds to throw an interception, with only 10 heading into Week 5. This means we may need to consider “No” as an option or delve into minus-odds.
Here are my two NFL interception props for Week 5:
NFL Interception Props for Week 5
- Jalen Hurts to Throw an Interception (+160, DraftKings)
- Dak Prescott to Throw an Interception(+110, bet365)

Jalen Hurts to Throw an Interception (+160)
This bet might seem like a dig at Jalen Hurts, but there’s a reason why we’re getting +160 odds to throw an interception, and that’s because … he doesn’t really throw them.
Since the start of last season, the Eagles QB has only thrown an INT in five of 23 games, including the playoffs. However, I think this is the week when he turns it over.
The Broncos defense has had their ups and downs this season, but one thing they do exceptionally well is get after the quarterback. Denver’s defense ranks No.1 in pressure rate per dropback while also having a 30% blitz rate, which is top eight in the NFL.
While Hurts has kept the ball out of the opponent’s hands, the fact remains that his accuracy and bad throws tend to pile up when facing pressure.
Hurts has three turnover-worthy plays in four games this season, and all have come when he was under pressure. In fact, since the start of last season, Hurts has had 22 TWPs, with 16 coming while under pressure and 12 while coming when seeing a blitz.
This checks both boxes for Denver.
Pair that with Hurts’ accuracy dropping off a cliff when seeing pressure (52% completions with pressure, 78% without since start of 2024), and I think this is the week where we see turnover positive regression kick in for the Broncos, who rank in the top 10 in total passes defended but with only one interception through four games.

Dak Prescott to Throw an Interception (+110)
I can’t think of a better time to fade Cowboys QB Dak Prescott.
Coming off a nearly flawless game against the Packers, the majority of the media has once again embraced Prescott as a top-tier QB, and while I do think he has his highs, I feel like we forgot some of the lows.
This is a big reason why I’m taking him to throw an interception in Week 5 against the Jets.
Some of these odds are matchup dependent, but look how the INT market has shifted on Prescott after one great game:
- Week 1: -175 to throw an INT
- Week 2: -110
- Week 3: -135
- Week 4: -160
- Week 5: +110
That is too much of a shift, even for Prescott, who has five turnover-worthy plays this season and an interception in two of four games.
The Jets defense hasn’t been as formidable as in previous years under Robert Saleh, but they blitz a lot (ranked 11th in the NFL) and are one of three teams without an interception this season.
I think there’s positive regression coming on the turnover front for the Jets.