Week 2 Lookahead Odds, Spreads for Every Game, Including Chargers vs Chiefs, Packers vs Bears, Titans vs Bills, More

Week 2 NFL Odds

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Chargers vs.

Chiefs

The Chiefs and Chargers both got off to winning starts in Week 1, although Kansas City certainly made more of a statement with its blowout win in Arizona.

Colts vs.

Jaguars

The Colts and Jaguars each enter this game winless … kind of? While Jacksonville blew a late lead in Washington, D.C., Indianapolis settled for one-half win with a tie in Houston.

Dolphins vs.

Ravens

Miami made a statement with its impressive win over the Patriots. Meanwhile, in New Jersey, the Ravens barely broke a sweat in Week by when they beat former quarterback Joe Flacco and the Jets.

Jets vs.

Browns

As mentioned above, the Jets didn't give Baltimore much of a fight. The Browns, though, showed that they're no slouch without Deshaun Watson. Cleveland is favored to get off to a 2-0 start.

Buccaneers vs.

Saints

The two biggest contenders in the NFC South will face off here. New Orleans escaped Atlanta with a one-point divisional win in Week 1, but it'll need to be much better to reach a 2-0 start and early division lead.

Patriots vs.

Steelers

This game features a matchup of perennial AFC contenders, although that wasn't the case last year. Pittsburgh is riding high coming off a big win over Cincinnati, while New England was humbled in Miami.

Panthers vs.

Giants

Can the Giants contend this season? It looks like they might after taking down last year's No. 1 seed in the AFC. Carolina, meanwhile, lost a heartbreaker at home to the Browns.

Commanders vs.

Lions

Washington held off the Jaguars last week, but the Lions offense looks pretty stout after dropping 35 points in a loss against the Eagles.

Seahawks vs.

49ers

Week 1 was not kind to the 49ers. Elijah Mitchell left the loss to the Bears with a knee injury, and Trey Lance's debut as the full-time starter was less than ideal.

Falcons vs.

Rams

This is an unenviable spot for the Falcons. The Rams are obviously better than they showed against the Bills, and they'll be looking to right the ship against a team that had very low expectations entering this season.

Cardinals vs.

Raiders

While Arizona looked out of its league against the Chiefs, the Raiders put up a solid fight against the Chargers. Both of these teams will be looking to avoid an 0-2 start, especially in their uber-competitive divisions.

Texans vs.

Broncos

The Texans looked like they might be improved from last season in their tie against the Colts. The Broncos offense might present a bigger test compared to Matt Ryan, though.

Bengals vs.

Cowboys

The Super Bowl Runner-up Curse is real. Cincinnati turned the ball over five times in Week 1 and still almost beat Pittsburgh. The Bengals will face a potentially tricky trip to Dallas in Week 2.

Bears vs.

Packers

Football's oldest rivalry is renewed on Sunday Night Football. While the Bears shocked the world by beating the 49ers, the Packers laid a major-league egg in Minnesota.

Titans vs.

Bills

While the Bills looked like one of the best teams in football in Week 1, the Titans … lost to the Giants. Buffalo will be up for its home opener, under the lights in Orchard Park.

Vikings vs.

Eagles

Two teams who impressed in Week 1 will close Week 2. Minnesota established itself as a contender in the NFC North by beating the Packers, while the Eagles offense thrived in Detroit.