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West Ham United vs. Manchester United Prediction, Pick, Premier League Odds for December 4

West Ham United vs. Manchester United Prediction, Pick, Premier League Odds for December 4 article feature image
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West Ham United (3-8-2) and Manchester United (6-4-3) will face off today at 3:00 p.m. EST at Old Trafford in Manchester.

Man U is favored at a -221 price, with the over/under set at 3.5 (+125o / -165u) goals.

Let's get into my West Ham vs. Man U prediction.

West Ham vs. Man U Prediction

Pick:Manchester United -1
My West Ham vs. Man U best bet is on the hosts to win by at least one.

West Ham vs. Man U Odds

West Ham Logo
Thursday, December 4, 2025
3:00 p.m. EST
-
Man U Logo
West Ham Odds
SpreadTotalMoneyline
+1.5
-160
3.5
+125o / -165u
+525
Man U Odds
SpreadTotalMoneyline
-1.5
+110
3.5
+125o / -165u
-221
Odds via bet365. Get up-to-the-minute SOCCER odds here.
bet365 Logo

West Ham vs. Man U Picks, Parlay

Pick:Manchester United Asian Handicap -1

Trailing 1-0 at halftime, Manchester United appeared headed for back-to-back league defeats last Sunday. However, tactical adjustments from Ruben Amorim transformed the match, with Joshua Zirkzee, Mason Mount and Diogo Dalot causing constant problems for Crystal Palace.

United ultimately secured a 2-1 win at Selhurst Park, a difficult venue where Palace had been unbeaten in 12 league matches and where the Red Devils had not won since July 2020.

Now the question is whether United can claim back-to-back victories in what looks like a more manageable fixture against West Ham. Despite being favorites last Monday, the Hammers stumbled at home to Everton.

West Ham plays a style similar to the Toffees’ and will likely look to strike on the counter at Old Trafford. Nuno Espírito Santo is slowly rebuilding the team’s spirit, but results remain a concern: the visitors have just 11 points from 13 Premier League matches. Only in 2010/11 (9 points) and 2017/18 (10 points) have they collected fewer at this stage. In the first of those seasons, they finished bottom and were relegated with 33 points.

Our in-house projections model, BETSiE, gives United over a 62% chance of victory. Given the matchup and the numbers, it’s reasonable to expect the hosts to win by at least a goal.

Playbook

West Ham vs. Man U Projections

Projected Chance of Winning

West HamDrawMan U
18.1%19.4%62.5%

Projected Total Goals

West HamTotal GoalsMan U
1.013.042.03

West Ham vs. Man U Betting Analysis

Manchester United hosts West Ham on Thursday after coming from behind to defeat Crystal Palace, with hopes of closing in on fourth place in the standings. The Hammers, meanwhile, sit just outside the relegation zone on goal difference after their loss to Liverpool.

A defeat at Old Trafford would almost certainly drop Nuno Espírito Santo’s side into the Premier League’s bottom three. Aside from Monday’s setback against Everton, United’s recent form has been solid, but the Red Devils now need to build on the improvements shown in the second half last weekend.

West Ham has secured only one away win this season, though it will hope to replicate last season’s success at Old Trafford.

Nevertheless, bookmakers are unanimous in their expectations. Ruben Amorim’s team is widely projected to take all three points, with the latest Manchester United vs. West Ham odds giving the hosts roughly a 70% chance of victory.

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