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Orioles vs Astros Prediction, Pick, MLB Odds for Friday July 17

Orioles vs Astros Prediction, Pick, MLB Odds for Friday July 17 article feature image
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Kiyoshi Mio-Imagn Images. Pictured: Orioles 1B Pete Alonso

The Houston Astros host the Baltimore Orioles on July 17, 2026. First pitch from Daikin Park is scheduled for 8:10 p.m. ET. The game will be broadcast on MASN.

The Astros are favored by -115 on the moneyline and by -1.5 on the run line. The Orioles are -105 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find our MLB picks and Orioles vs Astros prediction below, as well as probable pitchers, weather report, and more.


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Orioles vs Astros Prediction

  • Orioles vs Astros Pick: Pete Alonso Home Run (+300)

Our Orioles vs Astros best bet is on Pete Alonso to hit a homer tonight. Make sure to find the best odds by checking our live MLB odds page.


Orioles vs Astros Odds

Orioles Logo
Friday, Jul 17
8:10 p.m. ET
MASN
Astros Logo
Orioles Odds
SpreadTotalMoneyline
+1.5
-210
8.5
-120o / 100u
-105
Astros Odds
SpreadTotalMoneyline
-1.5
+175
8.5
-120o / 100u
-115
Odds via bet365. Get up-to-the-minute MLB odds here.
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  • Orioles vs Astros moneyline: Orioles -105, Astros -115
  • Orioles vs Astros over/under: 8.5 (-120o / +100u)
  • Orioles vs Astros spread: Orioles +1.5 (-210), Astros -1.5 (+175)

Orioles vs Astros Probable Pitchers

Dean Kremer (RHP, BAL)StatPeter Lambert (RHP, HOU)
1-2W-L8-5
-0.3fWAR (FanGraphs)1.1
4.09 / 4.48ERA / xERA3.14 / 3.35
6.78 / 3.34FIP / xFIP4.24 / 4.48
23.3K-BB%13.6
35.1GB%37.9
.184BABIP.233
90Stuff+92
101Location+100

Orioles vs Astros MLB Betting Preview, Prediction

Orioles slugger Pete Alonso is priced at bet365 at +300, implying a 25% chance to hit a homer tonight in Houston.

However, Action PRO projects him with 0.41 home runs, or a fair price closer to +144, which makes him a great pick.

At this time, he leads our prop edges for tonight's matchup against the Astros.

Alonso has 21 homers this season, and his splits favor him tonight. He's doing better on the road with a .262 average compared to .244 at home, and also against right-handed pitchers with an .878 OPS against .680 vs. lefties.

He's hit two dingers in his past five games, and we'll back him to get another one tonight against the Astros.

Pick: Pete Alonso Home Run (+300, bet365)


Orioles vs Astros Weather


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