The San Francisco Giants host the Boston Red Sox on June 21, 2025. First pitch from Oracle Park is scheduled for 4:05 p.m. EDT; the game will be broadcast on NESN.
Read our Red Sox vs Giants prediction and MLB same-game parlay picks below.
My Red Sox vs Giants Predictions, Parlay
- San Francisco Giants ML
- Rafael Devers 2+ Bases
Parlay Odds: +210 (BetMGM)
Red Sox vs Giants Odds
| Red Sox Odds | ||
|---|---|---|
| Run Line | Over/Under | Moneyline |
-1.5 +170 | 8 -102o / -118u | +100 |
| Giants Odds | ||
|---|---|---|
| Run Line | Over/Under | Moneyline |
+1.5 -210 | 8 -102o / -118u | -120 |
Red Sox vs Giants Projected Starting Pitchers
| RHP Brayan Bello (BOS) | Stat | RHP Landen Roupp (SFG) |
|---|---|---|
| 3-1 | W-L | 4-5 |
| 0.6 | fWAR (FanGraphs) | 0.7 |
| 3.49 / 4.84 | ERA / xERA | 3.99 / 3.85 |
| 4.27 / 4.33 | FIP / xFIP | 3.86 / 4.08 |
| 1.47 | WHIP | 1.46 |
| 6.5 | K-BB% | 11.0 |
| 53.6 | GB% | 45.5 |
| 95 | Stuff+ | 98 |
| 102 | Location+ | 107 |
Red Sox vs Giants Preview, Parlay Picks
San Francisco Giants Moneyline
We will ride with the home team in this matchup.
San Francisco is coming off a hard-fought loss in the first game of the series, but I love the bounce-back spot on Saturday.
The Red Sox will send right-hander Brayan Bello to the mound. The Giants will hand the ball to Landen Roupp.
Roupp has been outstanding this season with an ERA of 2.25 at home compared to 5.15 on the road.
I expect another strong effort from Roupp at home in this matchup.
Rafael Devers 2+ Bases
I love the value of this prop for Rafael Devers at plus money.
He struggled against his former team last night, going 0-for-4.
However, I love this buy-low spot for the Giants' new star.
Devers has 22 extra-base hits against right-handed pitching this season.
Red Sox vs Giants Parlay
- San Francisco Giants ML
- Rafael Devers 2+ Bases
Parlay Odds: +210 (BetMGM)
