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Reds vs Diamondbacks Prediction, Pick, MLB Odds for Saturday, August 22

Reds vs Diamondbacks Prediction, Pick, MLB Odds for Saturday, August 22 article feature image
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Aug 21, 2026; Phoenix, Arizona, USA; Arizona Diamondbacks center fielder Jorge Barrosa (1) celebrates with Jose Fernandez (11) and Ildemaro Vargas (6) after defeating the Cincinnati Reds in the first inning at Chase Field. Mandatory Credit: Rick Scuteri-Imagn Images

The Arizona Diamondbacks host the Cincinnati Reds on August 22, 2026. First pitch from Chase Field is scheduled for 8:10 p.m. EDT. The game will be broadcast on ARID.

Find my MLB picks and Reds vs Diamondbacks prediction below.


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Reds vs Diamondbacks Prediction

  • Reds vs Diamondbacks Pick: Diamondbacks ML (62c, Polymarket)

Reds vs Diamondbacks Polymarket MLB Odds


Reds vs Diamondbacks Probable Pitchers

Rhett Lowder (RHP, CIN)StatMichael Soroka (RHP, ARI)
4-8W-L8-3
1.3fWAR (FanGraphs)2.4
5.17 / 5.11ERA / xERA2.93 / 4.08
4.50 / 4.70FIP / xFIP2.87 / 3.61
8.8%K-BB%17.9%
41.7%GB%37.8%
.305BABIP.294
86Stuff+94
104Location+106

Reds vs Diamondbacks MLB Preview

Our own Sean Zerillo projects some value on the Diamondbacks ML in this game.

If you'd like to dive deeper into this matchup, I reccomend checking out BARTOLO, our new PRO baseball betting tool giving our Action PRO subscribers access to all the live data we use to project games each day.

Here's a sneak peek of what BARTOLO provides for just today's Reds-Diamondbacks game:

Opening Pitch: Find Saturday's Best Bets Using BARTOLO Image

Pick: Diamondbacks ML (62c, Polymarket)

Author Profile
About the Author

Tanner McGrath covers college basketball, college football and Major League Baseball at Action Network. He is a contributor to Payoff Pitch, Action Network’s Major League Baseball betting podcast. He's been working in the space for more than five years with past journalism experience in Canadian collegiate sports, finance and economics. He has an obsession with America East basketball, betting the Miami Marlins and sweating out home underdogs.

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