The New York Yankees (37-22) host the Cleveland Guardians (32-27) on Wednesday, June 4, 2025. First pitch from Yankee Stadium is scheduled for 7:05 p.m. ET; the game will be broadcast on Amazon Prime Video.
Continue below for my Guardians vs Yankees predictions and parlay picks for the middle game of this ALCS rematch.
Guardians vs Yankees Predictions, Parlay Picks
- Over 9
- Jose Ramirez 2+ Bases
Parlay Odds: +250 (BetMGM)
Cleveland Guardians vs New York Yankees Odds, Lines
| Guardians Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -124 | 9 -103o / -118u | +163 |
| Yankees Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +102 | 9 -103o / -118u | -195 |
Guardians vs Yankees Projected Starting Pitchers
| RHP Luis Ortiz (CLE) | Stat | RHP Clarke Schmidt (NYY) |
|---|---|---|
| 2-6 | W-L | 2-2 |
| 0.7 | fWAR (FanGraphs) | 0.6 |
| 4.40/4.97 | ERA /xERA | 3.95/3.07 |
| 3.96/3.74 | FIP / xFIP | 4.02/4.21 |
| 1.43 | WHIP | 1.27 |
| 13.2 | K-BB% | 12.3 |
| 47.0 | GB% | 35.3 |
| 98 | Stuff+ | 101 |
| 96 | Location+ | 102 |
Guardians vs Yankees Preview, Parlay
Over 9
We should see a lot of runs in Wednesday's matchup.
New York will send right-hander Clarke Schmidt to the mound. Schmidt has posted a 3.95 ERA this season and has struggled against this Guardians lineup. Cleveland boasts a .360 batting average against Schmidt in 50 team at-bats.
Luis Ortiz will toe the rubber for the Guardians. Ortiz has been one of the worst pitchers in baseball on the road this season, with a 6.39 ERA over 31 innings. New York is batting .333 against Ortiz in 42 at-bats.
Jose Ramirez 2+ Bases
The All-Star third baseman is a two-base threat every time he steps to the plate.
Ramirez has outstanding numbers against Schmidt, batting .429 in 14 at-bats, including three extra-base hits.
The veteran is poised to continue his success against Schmidt.
Guardians vs Yankees Same-Game Parlay
- Over 9 Total Runs
- Jose Ramirez 2+ Bases
Parlay odds: +250 (BetMGM)
Guardians vs Yankees Betting Trends
