The Athletics host the Cleveland Guardians on June 21, 2025. First pitch from Sutter Health Park is scheduled for 10:05 p.m. EDT; the game will be broadcast on NBCS-CA.
Read our Guardians vs Athletics prediction and MLB player prop pick below.
My Guardians vs Athletics Prediction
- Guardians vs Athletics Picks: Kyle Manzardo Over 0.5 Doubles (+375, bet365)
My Guardians vs Athletics best bet is on Kyle Manzardo's doubles prop. Make sure to find the best odds by checking our live MLB odds page.
Guardians vs Athletics Odds
| Guardians Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +125 | 9.5 -105o / -115u | -130 |
| Athletics Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -150 | 9.5 -105o / -115u | +110 |
Alex Kolodziej’s Guardians vs Athletics Preview
Cleveland Guardians Player Prop
For this Saturday’s Guardians vs. Athletics matchup, our top MLB pick centers on Kyle Manzardo to hit a double.
My morning routine is simple: Let the dogs out, start the coffee pot, check PRO’s top picks to hit a double.
I’ve been tracking the doubles market throughout the day Saturday, and Manzardo’s odds have shifted from +350 to +375 (bet365), indicating a favorable moment to get down on this bet.
According to our projections, Manzardo is expected to record approximately 0.33 doubles in the game, which, when combined with the current price of +375, presents an estimated 7.1% value edge over the market.
While Manzardo is widely recognized for his power-hitting abilities, the market has inflated his chances of hitting a home run, especially considering Sutter Health Field is a very hitter-friendly environment.
Home run odds appear overpriced, making the double bet a sharper alternative.
Our advanced models predict Manzardo will maintain a strong slugging performance against the Athletics this weekend. It’s also worth noting that Manzardo hit a double last Saturday for us after we recommended him at +550 odds — meaning, if he hits one again today, I will have no other choice than to call every Saturday from here on out the rest of the regular season “Kyle Manzardo Double Day.”
Pick: Kyle Manzardo Over 0.5 Doubles (+375, bet365)
