The Chicago Cubs host the Houston Astros on May 24, 2026. First pitch from Wrigley Field is scheduled for 2:20 p.m. ET. The game will be broadcast on SCHN.
The Cubs are favored by -175 on the moneyline and by -1.5 on the run line. The Astros are +144 on the moneyline and +1.5 on the run line. The total is set at 7 runs.
Find my MLB picks and Astros vs Cubs prediction below, as well as probable pitchers, weather report, and more.
Astros vs Cubs Prediction
- Astros vs Cubs Pick: Alex Bregman Home Run (+870)
My Astros vs Cubs best bet is on Alex Bregman to hit a homer this afternoon. Make sure to find the best odds by checking our live MLB odds page.
Astros vs Cubs Odds
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -155 | 7 -113o / -106u | +144 |
| Cubs Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +128 | 7 -113o / -106u | -175 |
- Astros vs Cubs moneyline: Astros +144, Cubs -175
- Astros vs Cubs over/under: 7 (-113o / -106u)
- Astros vs Cubs spread: Astros +1.5 (-155), Cubs -1.5 (+128)
Astros vs Cubs Probable Pitchers
| RHP Peter Lambert (HOU) | Stat | LHP Shota Imanaga (CHC) |
|---|---|---|
| 2-4 | W-L | 4-4 |
| 0.7 | fWAR (FanGraphs) | 1.3 |
| 3.57 / 3.41 | ERA / xERA | 3.38 / 3.34 |
| 3.29 / 3.85 | FIP / xFIP | 3.38 / 3.47 |
| 14.6 | K-BB% | 19.1 |
| 46.2 | GB% | 37.6 |
| .244 | BABIP | .252 |
| 92 | Stuff+ | 93 |
| 98 | Location+ | 107 |
Astros vs Cubs MLB Betting Preview
By Derek Carty
THE BAT X is forecasting 0.14 home runs for Cubs 3B Alex Bregman against his former team, the Astros. Oddsmakers are implying 0.10 home runs, so I believe there is value here.
If you take the over, you'd be projected to win 12% of the time, resulting in a 29% ROI with an expected value of $29.36 (based on a $100 wager). This play is good down to at least +793.
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Pick: Alex Bregman Home Run (+870, DraftKings)
