The Philadelphia Phillies host the Houston Astros on September 9, 2026. First pitch from Citizens Bank Park is scheduled for 6:40 p.m. ET. The game will be broadcast on SCHN.
The Phillies are favored by -158 on the moneyline and by -1.5 on the run line. The Astros are +134 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.
Find my MLB picks and Astros vs Phillies prediction below, as well as probable pitchers, weather report, and more.
Astros vs Phillies Prediction
- Astros vs Phillies Pick: NRFI (-128)
My Astros vs Phillies best bet is no runs scored in the first inning. Make sure to find the best odds by checking our live MLB odds page.
Astros vs Phillies Odds
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -152 | 8.5 108o / -132u | +134 |
| Phillies Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +126 | 8.5 108o / -132u | -158 |
- Astros vs Phillies moneyline: Astros +134, Phillies -158
- Astros vs Phillies over/under: 8.5 (+108o / -132u)
- Astros vs Phillies spread: Astros +1.5 (-152), Phillies -1.5 (+126)
Astros vs Phillies Probable Pitchers
| Hunter Brown (RHP, HOU) | Stat | Cristopher Sanchez (LHP, PHI) |
|---|---|---|
| 5-3 | W-L | 16-5 |
| 1.2 | fWAR (FanGraphs) | 5.9 |
| 3.31 / 3.53 | ERA / xERA | 2.58 / 3.23 |
| 4.18 / 3.88 | FIP / xFIP | 2.59 / 2.56 |
| 12.9 | K-BB% | 21.9 |
| 55.5 | GB% | 58.2 |
| .269 | BABIP | .333 |
| 104 | Stuff+ | 117 |
| 95 | Location+ | 97 |
Astros vs Phillies MLB Betting Preview, Prediction
The Phillies will host the Astros on Wednesday night in the second of a three-game interleague set at Citizens Bank Park in Philadelphia.
We’ve got an excellent pitching matchup in this game: Cristopher Sanchez vs. Hunter Brown.
Sanchez is still making his Cy Young case, running a 2.58 ERA with 207 strikeouts on the season, including a 2.11 ERA with 50 Ks over his past 42 frames (since the start of August).
Though not as dominant as Sanchez, Brown has been very good since returning from injury in mid-June, with a 3.66 ERA and 76 strikeouts across 76 innings.
I expect a pitcher’s duel between these two, especially in the very early part of the game.
Picks: NRFI (-128, FanDuel)
