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Brewers vs Cubs Prediction, Pick, MLB Odds for Wednesday, September 2

Brewers vs Cubs Prediction, Pick, MLB Odds for Wednesday, September 2 article feature image
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Pictured: Milwaukee Brewers starting pitcher Jacob Misiorowski. (Credit: Wendell Cruz-Imagn Images)

The Chicago Cubs host the Milwaukee Brewers on September 2, 2026. First pitch from Wrigley Field is scheduled for 7:40 p.m. EDT. The game will be broadcast on MARQ.

The Brewers are favored by -162 on the moneyline and by -1.5 on the run line. The Cubs are +136 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find my MLB picks and Brewers vs Cubs prediction below, as well as probable pitchers, weather report, and more.


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Brewers vs Cubs Prediction

  • Brewers vs Cubs Picks: Brewers -1.5 (+105), Brewers -0.5 F5 (-128) & Jackson Chourio 2+ TB (-125)

My Brewers vs Cubs best bets are on the Milwaukee run line in the first five innings and full game, as well as the Jackson Chourio total bases prop. Make sure to find the best odds by checking our live MLB odds page.


Brewers vs Cubs Odds

Brewers Logo
Wednesday, Sep 2
7:40 p.m. ET
MARQ
Cubs Logo
Brewers Odds
SpreadTotalMoneyline
-1.5
+106
8.5
-102o / -120u
-162
Cubs Odds
SpreadTotalMoneyline
+1.5
-128
8.5
-102o / -120u
+136
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Brewers vs Cubs moneyline: Brewers -162, Cubs +135
  • Brewers vs Cubs over/under: 8.5 (-102o / -120u)
  • Brewers vs Cubs spread: Brewers -1.5 (+106), Cubs +1.5 (-128)

Brewers vs Cubs Probable Pitchers

Jacob Misiorowski (RHP, MIL)StatDavid Peterson (LHP, CHC)
14-5W-L7-7
5.7fWAR (FanGraphs)1.3
1.73/2.01ERA / xERA5.11/4.90
2.15/2.16FIP / xFIP4.06/4.03
32.7%K-BB%10.3%
44.5%GB%50.3%
.226BABIP.323
128Stuff+89
101Location+102

Brewers vs Cubs MLB Betting Preview

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Milwaukee Brewers Betting Preview

The Brewers will send out their unicorn ace, Jacob Misiorowski, who has quickly established himself as one of baseball’s budding stars.

Misiorowski currently ranks atop the Major Leagues in several pitching metrics, including ERA (1.73), WHIP (0.75) and strikeouts (222 Ks).

He boasts a dynamic high-velocity pitching delivery built on elite lower-body mechanics, a massive stride, and exceptional extension.

Standing at 6-foot-7, Misiorowski utilizes his tremendous stride length to his advantage by achieving a roughly 7.5-foot extension down the mound.

For a guy who routinely registers 102-105 mph velocity on his four-seam fastball, Misiorowski’s remarkable extension shortens the baseball’s travel distance, giving hitters a reaction time equivalent to a 108 mph fastball.

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Chicago Cubs Betting Preview

While Milwaukee's star hurler is borderline unhittable right now, Cubs’ veteran left-hander David Peterson has not had the same luck.

Peterson has recorded a 5.11 ERA, with a 1.52 WHIP, which could be a recipe for disaster, having to face the red-hot Brewers.


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Brewers vs Cubs Pick, Betting Analysis

Given the Brew Crew’s significant edge on the mound heading into this game, I feel confident backing Milwaukee to cover both its first-five and full-game runlines.

I will also be looking to target Brewers’ superstar OF Jackson Chourio to have a massive night at the plate.

In eight previous at-bats against Peterson, Chourio has recorded three hits — one of which was a home run.

Picks:

  • Brewers -1.5 (+105)
  • Brewers -0.5 F5 (-128)
  • Jackson Chourio 2+ TB (-125)

Brewers vs Cubs Weather


Get the latest coverage on MLB Weather.


Author Profile
About the Author

Ryan graduated from Providence College in 2016 with Bachelor Degrees in Business Economics & Mathematics. It was at Providence where Ryan really first found his passion for sports betting. For a lifelong sports fan with a knack for statistical analysis, he was instantly drawn to the fundamentals of the industry, specifically how sports betting markets functioned and fluctuated. In what primarily started as a recreational hobby, Ryan began studying the ins-and-outs of sports betting markets on a daily basis. He took to Twitter (now X), where he amassed a following for writing a sports betting blog that provided statistical analysis behind his wagers. In spite of seeking employment opportunities elsewhere post graduation, Ryan continued to follow his passion for the statistical analysis of sports betting wagers, eventually deciding to pursue a career in the sports betting industry.

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