Brewers vs Cubs Prediction, Pick, Odds for Wednesday

Brewers vs Cubs Prediction, Pick, Odds for Wednesday article feature image
Credit:

Jeff Hanisch-Imagn Images. Pictured:

The Chicago Cubs host the Milwaukee Brewers on on June 18, 2025. First pitch from Wrigley Field is scheduled for 8:05 p.m. ET; the game will be broadcast on MARQ.

Find my MLB betting preview and Brewers vs Cubs prediction below, as well as probable pitchers, betting trends, injury reports and more.

Quickslip

Header First Logo
Header Second Logo

My Brewers vs Cubs Prediction

  • Brewers vs Cubs pick: Jacob Misiorowski Over 4.5 Strikeouts (-125)

My Brewers vs Cubs best bet is on Jacob Misiorowski to go over his strikeout prop. Make sure to find the best odds by checking our live MLB odds page.


Brewers vs Cubs Odds

Brewers Logo
Wednesday, June 18
8:05 p.m. ET
MARQ
Cubs Logo
Brewers Odds
SpreadTotalMoneyline
+1.5
-170
8
-105o / -115u
+125
Cubs Odds
SpreadTotalMoneyline
-1.5
+140
8
-105o / -115u
-150
Odds via BetMGM. Get up-to-the-minute MLB odds here.
BetMGM Logo

Brewers vs Cubs Projected Starting Pitchers

Jacob Misiorowski (MIL)StatJameson Taillon (CHC)
1-0W-L7-3
0.1fWAR (FanGraphs)0.6
0.00 / 1.55ERA /xERA3.48 / 3.67
3.47 / 4.92FIP / xFIP4.59 / 3.95
0.80WHIP0.98
5.6K-BB%15.1
44.4GB%34.9
130Stuff+97
86Location+110

Brewers vs Cubs Prediction, Betting Analysis

Jacob Misiorowski came through for us in his debut, as he struck out five hitters.

However, he was also forced to leave the game early — despite not allowing a hit — thanks to him awkwardly rolling his ankle. That means he could've easily had a couple more strikeouts.

The fact that he was given full clearance to start in his next scheduled spot in the rotation tells me that he's good to go. All of the reasons I liked him last time out apply here, as well.

In his debut, Misiorowski posted a 31% CSW% and a 130 Stuff+ rating.

Pick: Jacob Misiorowski Over 4.5 Strikeouts (-125)


Moneyline

I don't have a play on the moneyline.


Run Line (Spread)

I also don't have a play on the run line.


Over/Under

While there's no value on the total, I'm targeting Jacob Misiorowski to record more than 4.5 strikeouts.


Brewers vs Cubs Betting Trends


Brewers vs Cubs Weather


Get the latest coverage on MLB Weather.

This site contains commercial content. We may be compensated for the links provided on this page. The content on this page is for informational purposes only. Action Network makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event.