Twins vs Royals Prediction, Pick, Odds for Saturday, September 6 article feature image
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Twins vs Royals Prediction, Pick, Odds for Saturday, September 6

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Pictured: Joe Ryan. (Credit: Bruce Kluckhohn-Imagn Images)

The Kansas City Royals host the Minnesota Twins on September 6, 2025. First pitch from Kauffman Stadium is scheduled for 7:15 p.m. EDT; the game will be broadcast on FOX.

Find my MLB betting preview and Twins vs Royals prediction below, as well as probable pitchers, betting trends, injury reports and more.

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Our Twins vs Royals Prediction

  • Twins vs Royals pick: Under 8

Our Twins vs Royals best bet is on the under total runs. Make sure to find the best odds by checking our live MLB odds page.


Twins vs Royals Odds

Twins Logo
Saturday, Sep 6
7:15 p.m. ET
FOX
Royals Logo
Twins Odds
SpreadTotalMoneyline
-1.5
+145
8
-110o / -110u
-120
Royals Odds
SpreadTotalMoneyline
+1.5
-175
8
-110o / -110u
+100
Odds via BetMGM. Get up-to-the-minute MLB odds here.
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Twins vs Royals Projected Starting Pitchers

RHP Joe Ryan (MIN)StatRHP Stephen Kolek (KCR)
13-7W-L4-5
3.6fWAR (FanGraphs)1.0
3.08/3.37ERA /xERA3.99/4.45
3.30/3.58FIP / xFIP4.13/4.32
0.97WHIP1.26
23.5%K-BB%9.2%
37.4%GB%51.9%
104Stuff+96
107Location+100

Twins vs Royals Prediction, Betting Analysis

The Minnesota Twins are priced as -120 favorites on the moneyline for Game 2 of their series with the Kansas City Royals, who check in as +100 underdogs. Oddsmakers set the total at 8 runs.

On Saturday, the pitching matchup features Joe Ryan for Minnesota and Stephen Kolek for Kansas City.

Kansas City struck first on Friday night, riding a Maikel Garcia two-run homer and 5 2/3 strong innings from Michael Wacha to a 2-1 victory.

This spot lines up with Evan Abrams’ “Series Unders: Off Low-Scoring Games” system, which looks to take advantage of early- or mid-series matchups that follow a low-scoring opener. The logic: when both teams come off quiet offensive nights, the market often expects a bounce-back in runs — but in practice, those bats tend to stay cold.

Friday’s opener produced just three total runs, and with Ryan’s strikeout upside matched against Kolek’s ground-ball approach, the setup points to another slower-paced contest. Add in the fact that both bullpens are well-rested after an easy night of work, and the case for a second straight under gets stronger.

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Evan Abrams / Bet Labs – Series Unders: Off Low-Scoring Games
betting on the Under
the series game # is between 2 and 10
the Home teams' 1 Game points scored streak is between 0 and 2
the Visiting teams' 1 Game points scored streak is between 0 and 2
the game is played during the Regular season
$18.387
WON
1402-1128-121
RECORD
55%
WIN%

Pick: Under 8 (-110, BetMGM)


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