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Mets vs Cubs Predictions, Parlay, Picks, Odds for Tuesday, September 23

Mets vs Cubs Predictions, Parlay, Picks, Odds for Tuesday, September 23 article feature image
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Nico Hoerner (Imagn Images)

The Chicago Cubs host the New York Mets on September 23, 2025. First pitch from Wrigley Field is scheduled for 7:40 p.m. EDT; the game will be broadcast on MARQ.

Find my MLB betting preview and Mets vs Cubs prediction below, as well as probable pitchers, betting trends, injury reports and more.

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My Mets vs Cubs Predictions, Parlay

  • Mets ML
  • Nico Hoerner 1+ Hit

Parlay Odds: +140 (via bet365)


Mets vs Cubs Odds

Mets Logo
Tuesday, Sep 23
7:40 p.m. ET
MARQ
Cubs Logo
Mets Odds
SpreadTotalMoneyline
+1.5
-230
7.5
-105o / -115u
-110
Cubs Odds
SpreadTotalMoneyline
-1.5
+190
7.5
-105o / -115u
-110
Odds via bet365. Get up-to-the-minute MLB odds here.
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Mets vs Cubs Projected Starting Pitchers

LHP David Peterson (NYM)StatRHP Cade Horton (CHC)
9-6W-L11-4
3.1fWAR (FanGraphs)2.2
3.98/4.44ERA /xERA2.66 3.82
3.47/3.69FIP / xFIP3.53 4.29
1.34WHIP1.10
12.1%K-BB%13.3%
55.0%GB%43.2%
90Stuff+96
102Location+101

Mets vs Cubs Preview, Parlay Picks

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Mets ML

We will ride with the road team in this prime-time affair tonight.

The Mets will treat this game like a playoff game as they are tied for the final wildcard position with the Cincinnati Reds. New York has struggled since the All-Star break and has fallen out of the playoff standings for the first time since May last week.

The good news for the Mets is that they still have a chance if they can run the table late in the season. Chicago has lost four consecutive games since clinching its first playoff berth since 2020, and New York is the more motivated team, boasting big-game experience across its roster.

Southpaw David Peterson will toe the rubber for the Mets. Peterson has been solid on the road this year with a record of 4-4 paired with an ERA of 3.76. I expect him to deliver a strong outing tonight and for the Mets' bats to enjoy success against rookie Cade Horton.


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Nico Hoerner 1+ Hit

The Cubs' second baseman leads the team in batting at .299 this season.

Hoerner has collected a team-best 171 hits and draws a favorable matchup tonight.

The 28-year-old has destroyed left-handed pitching, batting .358 in 134 at-bats.

Hoerner is 2-3 in his career against Peterson.


Mets vs Cubs Parlay

  • Mets ML
  • Nico Hoerner 1+ Hit

Parlay odds: +140 (via bet365)


Mets vs Cubs Betting Trends


Mets vs Cubs Weather


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