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Pirates vs Yankees Game 2 Prediction, Pick, Odds: Interleague Unders (Wednesday, July 22)

Pirates vs Yankees Game 2 Prediction, Pick, Odds: Interleague Unders (Wednesday, July 22) article feature image
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Jul 5, 2026; Bronx, New York, USA; New York Yankees pitcher Max Fried throws a live bullpen session before a game against the Minnesota Twins at Yankee Stadium. Mandatory Credit: John Jones-Imagn Images

The New York Yankees host the Pittsburgh Pirates on July 22, 2026. First pitch from Yankee Stadium is scheduled for 7:05 p.m. EDT. The game will be broadcast on SportsNet PT.

The Yankees are favored by -168 on the moneyline and by -1.5 on the run line. The Pirates are +142 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find my MLB picks and Pirates vs Yankees prediction below, as well as probable pitchers, weather report, and more.


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Pirates vs Yankees Prediction

  • Pirates vs Yankees Pick: Under 8.5

My Pirates vs Yankees best bet is on the Under. Make sure to find the best odds by checking our live MLB odds page.


Pirates vs Yankees Odds

Pirates Logo
Wednesday, Jul 22
7:05 p.m. ET
SportsNet PT
Yankees Logo
Pirates Odds
SpreadTotalMoneyline
+1.5
-150
8.5
-124o / 102u
+142
Yankees Odds
SpreadTotalMoneyline
-1.5
+125
8.5
-124o / 102u
-168
Odds via FanDuel. Get up-to-the-minute MLB odds here.
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  • Pirates vs Yankees moneyline: Pirates +142, Yankees -168
  • Pirates vs Yankees over/under: 8.5 (-124 / +102)
  • Pirates vs Yankees spread: Yankees -1.5 (+125), Pirates +1.5 (-150)

Pirates vs Yankees Game 2 Kalshi MLB Odds


Pirates vs Yankees Probable Pitchers

Bubba Chandler (RHP, PIT)StatMax Fried (LHP, NYY)
3-8W-L4-3
1.0fWAR (FanGraphs)1.9
4.77 / 4.14ERA / xERA3.21 / 2.63
4.59 / 5.12FIP / xFIP2.71 / 3.93
7.1%K-BB%12.9%
38.0%GB%48.8%
.271BABIP.250
104Stuff+106
100Location+101

Pirates vs Yankees MLB Betting Preview

This game triggered one of our Action PRO betting systems, powered by Evan Abrams:

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Evan Abrams / Bet Labs – Interleague Under Edge
the home money is between -260 and -110
the closing total is between 7 and 10
the home team's game number is between 22 and 161
the game is a Non-Conference game
the home team's win percentage is between 49% and 100%
the visitor team's win percentage is between 49% and 100%
betting on the Under
$9,522
WON
729-585-69
RECORD
55%
WIN%

This system targets Unders in interleague games where both teams are winning clubs, and the market sets a modest total between seven and 10 runs.

The setup leverages:

  • Solid teams (49–100% win rate) facing unfamiliar lineups and pitchers.
  • Later-season matchups (game 22+), when teams settle into pitching rhythms.
  • Home teams favored (moneyline -260 to -110), suggesting stronger bullpens.
  • Undervalued run suppression due to lack of offensive familiarity

The result: profitable unders in tighter, more disciplined matchups between quality teams with limited recent exposure to each other.

Pick: Under 8.5

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Pirates vs Yankees Weather


Get the latest coverage on MLB Weather.

Pirates vs Yankees Game 2 Betting Trends


Pirates vs Yankees Game 2 Prop Projections

Author Profile
About the Author

Tanner McGrath covers college basketball, college football and Major League Baseball at Action Network. He is a contributor to Payoff Pitch, Action Network’s Major League Baseball betting podcast. He's been working in the space for more than five years with past journalism experience in Canadian collegiate sports, finance and economics. He has an obsession with America East basketball, betting the Miami Marlins and sweating out home underdogs.

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