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Red Sox vs Blue Jays Prediction, Pick, Odds for Thursday, September 25

Red Sox vs Blue Jays Prediction, Pick, Odds for Thursday, September 25 article feature image
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Pictured: Alex Bregman

The Toronto Blue Jays host the Boston Red Sox on September 25, 2025. First pitch from Rogers Centre is scheduled for 7:07 p.m. EDT; the game will be broadcast on SNET.

Find my MLB betting preview and Red Sox vs Blue Jays prediction below, as well as probable pitchers, betting trends, injury reports and more.

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My Red Sox vs Blue Jays Prediction

  • Red Sox vs Blue Jays picks: Red Sox ML +115

My Red Sox vs Blue Jays best bet is on the Red Sox moneyline. Make sure to find the best odds by checking our live MLB odds page.


Red Sox vs Blue Jays Odds

Red Sox Logo
Thursday, Sep 25
7:07 p.m. ET
SNET
Blue Jays Logo
Red Sox Odds
SpreadTotalMoneyline
+1.5
-180
8
100o / -120u
+115
Blue Jays Odds
SpreadTotalMoneyline
-1.5
+155
8
100o / -120u
-135
Odds via bet365. Get up-to-the-minute MLB odds here.
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Red Sox vs Blue Jays Projected Starting Pitchers

Brayan Bello (BOS)StatLouis Varland (TOR)
11-8W-L4-3
1.9fWAR (FanGraphs)1.1
3.34ERA /xERA3.10/4.15
4.48FIP / xFIP3.24/3.14
1.24WHIP1.22
9.6K-BB%17.2
49.5GB%54.2
97Stuff+111
102Location+103

Red Sox vs Blue Jays Prediction, Betting Analysis

This MLB betting system focuses on regular-season division games where a team is coming off a dominant win against a divisional rival. The strategy leverages both momentum and familiarity in rivalry matchups, targeting teams with a win percentage between 16% and 75% to avoid extreme outliers and heavily overvalued favorites.

It zeroes in on spots where teams are priced between -135 and +290 and are fresh off a victory by 6–21 runs, signaling a strong recent performance without being unsustainable. By layering in moderate home or road streaks (-6 to +7 games) and the context of back-to-back division matchups, this system looks to capitalize on situations where the betting market hasn’t fully adjusted to the impact of a recent blowout win.

Pick: Red Sox ML


Moneyline

Take the Red Sox on the moneyline tonight.


Run Line (Spread)

No play on the run line.


Over/Under

No play on the total.


Red Sox vs Blue Jays Betting Trends


Red Sox vs Blue Jays Weather


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Action Network is a team of seasoned sports betting experts specializing in a broad range of sports, from the NFL and NBA to less mainstream options like cricket and darts. Their staff includes well-known analysts like Sean Koerner and Stuckey, recognized for their accurate predictions and deep sports knowledge. The team is dedicated to delivering expert analysis and daily best bets, ensuring bettors are well-informed across all major sports.

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