Padres vs Blue Jays Predictions, Parlay, Picks, Odds for Thursday, May 22

Padres vs Blue Jays Predictions, Parlay, Picks, Odds for Thursday, May 22 article feature image
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Pictured: Fernando Tatis Jr. (Credit: Denis Poroy-Imagn Images)

The Toronto Blue Jays host the San Diego Padres on May 22, 2025. First pitch from Rogers Centre is scheduled for 1:07 p.m. EDT; the game will be broadcast on SDPA.

Read our Padres vs Blue Jays prediction and same-game parlay picks below.

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My Padres vs Blue Jays Predictions, Parlay

  • Fernando Tatis Jr. Hit
  • Padres ML

Parlay odds: +105 (Fanatics)


Padres vs Blue Jays Odds

Padres Logo
Thursday, May 22
1:07 p.m. ET
SDPA
Blue Jays Logo
Padres Odds
SpreadTotalMoneyline
-1.5
+140
9
-102o / -118u
-120
Blue Jays Odds
SpreadTotalMoneyline
+1.5
-170
9
-102o / -118u
+100
Odds via BetMGM. Get up-to-the-minute MLB odds here.
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Padres vs Blue Jays Projected Starting Pitchers

RHP Stephen Kolek (SDP)StatRHP Bowden Francis (TOR)
2-1W-L2-6
0.2fWAR (FanGraphs)-0.5
2.33 / 3.23ERA /xERA5.63 / 6.03
4.32 / 3.43FIP / xFIP6.49 / 4.63
1.14WHIP1.40
13.3K-BB%11.4
58.2GB%34.5
96Stuff+93
101Location+105

Padres vs Blue Jays Preview, Parlay Picks

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Fernando Tatis Jr. Hit

I'm backing the Padres to bounce back after Wednesday's gross, 14-0 loss behind superstar player Fernando Tatis Jr.

Tatis went 0-for-4 during the shutout. He's only had four hitless games this season, but he's followed up all four with a hit in the next game.

He also has substantial numbers against Bowden Francis' pitch mix.

I expect Francis to struggle against Tatis and San Diego's star-studded lineup.


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Padrres ML

The Padres have been struggling lately, currently riding a five-game losing streak. They have yet to score in Toronto, but that should change on Thursday.

The Padres are positioned to win today thanks to their better hitting and starting pitching.

As mentioned, Francis is having a tough season, with a 2-6 record behind an ERA over five.

I'm backing the better team to snap their losing streak and get out of Canada with a win on Thursday.


Padres vs Blue Jays Parlay

  • Fernando Tatis Jr. Hit
  • Padres ML

Parlay odds: +105 (Fanatics)


Padres vs Blue Jays Betting Trends


Padres vs Blue Jays Weather


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