The Chicago Cubs host the Seattle Mariners on June 22, 2025. First pitch from Wrigley Field is scheduled for 2:20 p.m. EDT; the game will be broadcast on ROOT Sports NW.
Read our Mariners vs Cubs prediction and MLB pick below.
My Mariners vs Cubs Prediction
- Mariners vs Cubs Picks: Over 11.5 (-102, BetMGM)
My Mariners vs Cubs best bet is on the Over. Make sure to find the best odds by checking our live MLB odds page.
Mariners vs Cubs Odds
| Mariners Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +135 | 11.5 -102o / -118u | -120 |
| Cubs Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -160 | 11.5 -102o / -118u | -100 |
Brit Devine’s Mariners vs Cubs Preview
The total of this game opened at 12.5 or 12, and it's been bet down to a level where I want to pounce on the Over.
I bet the Over on Saturday, which cashed. While we have better pitching on Sunday (hence the total dropping), the hitting conditions are as good as those on Saturday, which saw 17 runs scored between these two teams.
We’re expecting temperatures over 90 degrees with high humidity and a steady 15-plus MPH wind blowing out toward center field (with gusts approaching 30 MPH).
This is one of those weather games that happen so infrequently that the books don’t know how to price them — I would make this total at least 12.5.
Pick: Over 11.5 (-102, BetMGM)
