Rays vs Red Sox Prediction, Odds, Picks, MLB Betting Preview

Rays vs Red Sox Prediction, Odds, Picks, MLB Betting Preview article feature image
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Credit: Imagn Images. Pictured: Tampa Bay Rays SP Ryan Pepiot (left), Boston Red Sox SP Lucas Giolito (right).

The Boston Red Sox host the Tampa Bay Rays on June 10, 2025. First pitch from Fenway Park is scheduled for 7:10 p.m. ET; the game will be broadcast on NESN and MLB.TV.

The Red Sox enter as -115 favorites on the moneyline with the over/under sitting at 9.

Read our Rays vs Red Sox prediction and MLB pick below.

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Tampa Bay Rays vs Boston Red Sox Prediction, Picks

  • Rays vs Red Sox Pick: Over 9.5 (+100, BetMGM)

My Red Sox vs. Rays best bet is on both teams to go over the total. Make sure to find the best odds by checking our live MLB odds page.


Rays vs Red Sox Odds, Line, Spread

Rays Logo
Tuesday, June 10
7:10 p.m. ET
MLB.TV
Red Sox Logo
Rays Odds
Run LineTotalMoneyline
-1.5
+152
9
-110o / -110u
-106
Red Sox Odds
Run LineTotalMoneyline
+1.5
-187
9
-110o / -121u
-115
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo

Rays vs Red Sox Projected Pitchers

RHP Ryan Pepiot (TBR)StatRHP Lucas Giolito (BOS)
3-5W-L1-1
0.7fWAR (FanGraphs)0.1
3.20 / 4.24ERA / xERA6.42 / 5.80
4.35 / 4.02FIP / xFIP4.76 / 4.28
1.13WHIP1.63
13.9%K-BB%10.7%
37.7%GB%39.6%
107Stuff+88
104Location+104

Rays vs Red Sox MLB Betting Preview

These are two starting pitchers that I’m very low on.

Red Sox starter Lucas Giolito is a mess (6.42 ERA, 5.80 xERA, 88 Stuff+) and is consistently prone to complete blow-ups — he allowed eight runs across seven hits in his last outing against the Angels.

Meanwhile, Rays starter Ryan Pepiot is overperforming (3.20 ERA, 4.24 xERA) and due for significant regression. He’s lost some swing-and-miss stuff (21% strikeout rate), so he’s run into a homer-problem as a fly-ball-heavy pitcher (1.42 HR/9, 37% GB rate).

He allowed six earned runs on nine hits across six innings in his last start against Boston, a 7-4 loss on April 15. The Red Sox bats could get to him again on Tuesday.

Of arguably greater importance, both these bullpens are gassed.

The Red Sox have deployed almost all their relievers multiple times in the past four days, including:

Pitcher9-June8-June7-June
Aroldis Chapman15311
Greg Weissert1012
Brennan Bernardino1621
Zack Kelly231524

And the Rays are in a similar situation:

Pitcher9-June8-June7-June
Pete Fairbanks3013
Garrett Cleavinger1412
Manuel Rodriguez2117
Kevin Kelly7
Mason Montgomery1311
Eric Orze16526

Fenway is always a hitter-friendly park, and the weather should be reasonably hitter-friendly. The Rays’ offense is red-hot (121 wRC+ over the past two weeks), and the Red Sox aren’t far behind (112 wRC+).

Behind two struggling starting pitchers, two exhausted bullpens, and two white-hot lineups in a great ballpark, I expect plenty of runs in Boston on Tuesday.

Our guy Sean Zerillo projects 9.9 runs for this matchup.

Pick: Over 9.5 (+100 · BetMGM)


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About the Author
Tanner McGrath covers college basketball, college football and Major League Baseball at Action Network. He is a contributor to Payoff Pitch, Action Network’s Major League Baseball betting podcast. He's been working in the space for more than five years with past journalism experience in Canadian collegiate sports, finance and economics. He has an obsession with America East basketball, betting the Miami Marlins and sweating out home underdogs.

Follow Tanner McGrath @tannerstruth on Twitter/X.

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