Thunder vs. Spurs Odds & Betting Predictions - October 21, 2026

Thunder at Spurs

1:30 am • NBC/Peacock
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Thunder at Spurs Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Thunder
0-0
+2.5
-1.5-105
o230.5-114
-118
Spurs
0-0
u230.5
+1.5-115
u230.5-114
-104
location pinWednesday 1:30 a.m.
October 21, 2026
Frost Bank CenterSan Antonio
Thunder vs. Spurs Expert Picks
YBK Picks.com
Last 30d: 40-43-1 (-11.8u)
OKC -1.5-105
2u
Under 233.5-110
0.55u
Doug Ziefel
Doug Ziefel
Last 30d: 361-409-7 (+9.8u)
OKC +102
0.49u
Joe Dellera
Joe Dellera
Last 30d: 15-24-0 (+6.3u)
D.Harper o4.5 Rebs-117
1u
Spurs look like they're going to run a starting lineup of Fox/Castle/Harper/Vassell/Wemby which significantly cuts down on their size. Harper is a ball hawk as we saw during the postseason and I expect him to see minutes around 30 this season as a starter. He averaged 4.9 rpg when playing 25+ minutes and during the Playoffs it was 6.2. I'll bite again here against OKC.
Ryan Minion
Ryan Minion
Last 30d: 228-246-5 (-15.5u)
S.Castle o27.5 Pts+Rebs+Ast-120
1.2u
S.Castle o6.5 Ast-108
1.1u
OldSchool0909
Last 30d: 45-60-2 (-9.4u)
OKC +1.5-109
1u
Collin Whitchurch
Collin Whitchurch
Last 30d: 97-132-3 (+0.5u)
D.Harper o4.5 Rebs-115
0.57u
OKC -102 (1Q)
0.51u
Jim Turvey
Jim Turvey
Last 30d: 30-36-0 (+2.2u)
OKC +110 (1Q)
0.5u
Can get 10 extra cents going to PMs here! Three guard lineup hater here. Don’t mind OKC in the Race to X markets as well and also just fading Spurs in general today
Sandy Plashkes
Sandy Plashkes
Last 30d: 101-97-2 (+28.1u)
J.McCain o9.5 Pts-116
1.16u
The Degenerates
The Degenerates
Last 30d: 50-47-2 (-0.3u)
J.Williams o17.5 Pts-105
1.05u
Kyle Murray
Kyle Murray
Last 30d: 143-135-10 (+13.7u)
C.Wallace u1.5 3pt M-109
1.09u
J.McCain o1.5 Ast+175
0.75u
D.Harper u20.5 Pts+Rebs-105
1.05u
J.Champagnie u4.5 Rebs+115
0.87u
C.Wallace u3.5 Rebs-122
1.22u
Brian Bitler
Brian Bitler
Last 30d: 67-73-4 (-13.5u)
OKC +1.5-102
3u
Brandon Kravitz
Brandon Kravitz
Last 30d: 50-60-1 (-0.7u)
OKC +2.5-109
1.09u
I think NBA bettors have a tendency to overvalue the home opener in the NBA, yes there’s a lot of energy in the building – if that’s your angle, bet a first quarter…but I think this line should be more of a pick em. I have the Thunder rated higher coming into the season – yes, the spurs match up well against them, and if they meet in the playoffs, that will certainly be a factor in my analysis – but the Thunder have been waiting months to get some payback for the WCF…that’s the sort of motivation that I think can carry for 4 quarters. I like the spurs, love the roster, love the build, but there’s a chance they regress pretty hard this season – at least in the outset. This will be only one in a small handful of times we see the Thunder listed as dogs this season.
Allan Lem
Allan Lem
Last 30d: 41-31-1 (+0.9u)
J.Williams u28.5 Pts+Rebs+Ast-122
0.61u
The Pick Don
The Pick Don
Last 30d: 6-9-1 (-6.6u)
OKC -110
1.65u
San Antonio is a very good basketball team, and this isn’t me trying to take away from what they accomplished last season. However, the Spurs finished first in our luck ratings, and I think their run to the NBA Finals has their market perception near its peak. A team can be legitimately great and still have benefited from things breaking its way. I’m betting that we’re getting a better opportunity to back Oklahoma City because of how last season ended. This is also a major revenge spot for the Thunder after San Antonio knocked them out in seven games. We have to remember how compromised Oklahoma City was during that series, with Jalen Williams and Ajay Mitchell both missing time. Those two are now back at full strength, which gives this offense more creation and takes pressure off Shai Gilgeous-Alexander. Having Williams healthy is especially important against a defense anchored by Victor Wembanyama. You need multiple players who can create an advantage rather than asking Shai to manufacture everything. Losing Lu Dort obviously hurts defensively, but I’m less concerned about his departure than some people seem to be. His offense became a real issue in the playoffs, to the point that his minutes were reduced because of his inconsistency. Against a defense like San Antonio’s, having someone opponents are comfortable helping off can make life much harder for everyone else. There is a reasonable argument that different lineup combinations can improve Oklahoma City’s spacing and offensive flexibility. With Cason Wallace and Alex Caruso still available on the perimeter and Chet Holmgren protecting the rim, I still view this as an elite defensive group. Another matchup worth watching is San Antonio’s smaller starting lineup with Tobias Harris sidelined. The Spurs are expected to start Fox, Castle, Harper, Vassell and Wembanyama, giving Oklahoma City an opportunity to use its size with Holmgren and Isaiah Hartenstein. I want to see the Thunder make that lineup defend size, compete on the offensive glass and force Wembanyama to account for more than just the ball handler. Harris’ absence also takes away another experienced forward San Antonio could use to balance those groups. Revenge alone doesn’t win a basketball game, but it adds to a spot I already like. The Spurs deserve respect, and Wembanyama is an enormous challenge. Still, I trust Oklahoma City’s healthier core, defensive versatility and ability to create through Shai and Williams. I’m backing the Thunder to get this season started with a win.
Mjaybrod
Mjaybrod
Last 30d: 53-80-1 (-25.7u)
C.Holmgren o22 Pts+Rebs+Ast-113
1u
Alex Hinton
Alex Hinton
Last 30d: 82-96-3 (-12.2u)
J.Williams o1.5 3pt M+150
1u
D.Harper o19.5 Pts+Rebs-125
1u
Nick Griffith
Last 30d: 48-42-0 (+7.0u)
D.Harper o1.5 3pt M+133
0.75u
Bryan Fonseca
Bryan Fonseca
Last 30d: 3-2-0 (+0.6u)
D.Harper o23.5 Pts+Rebs+Ast-108
1u
Buckets Podcast
Buckets Podcast
Last 30d: 2-1-0 (+0.4u)
D.Harper o23.5 Pts+Rebs+Ast-108
1u
@bryanfonseca ⭐️⭐️⭐️ https://youtu.be/jtlsYkg8S7g?is=guwdWjYpjtMWE4in
C.Holmgren u13.5 Pts-112
1u
@FiddlesPicks ⭐️⭐️⭐️ https://youtu.be/jtlsYkg8S7g?is=guwdWjYpjtMWE4in
J.Champagnie o1.5 3pt M-170
0.25u
Wags Wins
Wags Wins
Last 30d: 240-239-3 (-10.7u)
OKC +110
1u
Charlie DiSturco
Charlie DiSturco
Last 30d: 104-193-1 (+13.9u)
J.Williams o1.5 3pt M+165
0.25u
J.Williams o2.5 3pt M+500
0.1u

Thunder vs. Spurs Previews & Analysis

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Prop Odds Comparison

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Thunder vs. Spurs Public Betting Percentages

Away Logo

Thunder

Public

36%

Bets%

64%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Spurs
N/AN/AN/AN/AN/A
Thunder
N/AN/AN/AN/AN/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Spurs
N/AN/AN/AN/AN/A
Thunder
N/AN/AN/AN/AN/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Spurs
N/AN/AN/AN/AN/A
Thunder
N/AN/AN/AN/AN/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 17thSACW 126-97-13.5 WU 230.5SAS -650
Oct 15thPHXW 123-103-1.5 WO 222SAS -535
Oct 13th@UTAL 109-119+6 LU 228.5UTA +180
Oct 11th@PHXL 98-102-7.5 LU 224.5PHX -275
Oct 9thATLL 116-123-8.5 LO 227.5ATL -270

Thunder vs. Spurs Injury Updates

Thunder Injuries

  • Nikola Topic
    PG

    Topic is out with back

    Out

  • Thomas Sorber
    C

    Sorber is out with knee

    Out

  • Otega Oweh
    SG

    Oweh is out with achilles

    Out

Spurs Injuries

  • Tobias Harris
    PF

    Harris is out with calf

    Out

  • Jayden Quaintance
    PF

    Quaintance is out with knee

    Out

Thunder vs. Spurs Odds Comparison

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Thunder at Spurs Team Totals

MatchupOverUnder
Thunder
0-0
N/A
N/A
Spurs
0-0
N/A
N/A