Saturday College Basketball Picks for Notre Dame vs. Syracuse, Iowa State vs. Kansas

College basketball Saturday is loaded with picks and best bets, including both small-school matchups and big-time games.

Here, we're diving into the top predictions for a pair of Power Five tilts in the Syracuse Orange vs. Notre Dame Fighting Irish and Iowa State Cyclones vs. Kansas Jayhawks.

One of Bet Labs' top college basketball betting systems has picks on both games, and you're not going to believe one of the filters that the trend accounts for: Fading the public.

Using our college basketball betting data and systems, here are the two best bets against the spread the model spit out for Syracuse vs. Notre Dame and Iowa State vs. Kansas

College basketball odds and data as of Saturday morning.

College Basketball Best Bets

Notre Dame vs. Syracuse (-5.5)

7 p.m. ET 

Bet Labs' Fade the Public in Big Conferences (PRO) system has a clear best bet on this ACC matchup.