Missouri vs. Oklahoma Odds & Betting Predictions - November 22, 2025
Missouri at Oklahoma
5:00 pm • ABCMissouri at Oklahoma Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Missouri 8-5 | +9 | +4.5-112 | o42.5-115 | +172 |
Oklahoma 10-3 | u54.5 | -4.5-108 | u43-110 | -210 |

Gaylord Family Oklahoma Memorial StadiumNorman
Missouri vs. Oklahoma Expert Picks
The Propfessor
Last 30d: 50-43-0 (+14.4u)
X.Robinson u54.5 Rush Yds-115
0.65u
Vegas Refund
Last 30d: 72-68-0 (-2.4u)
MIZ +5.5+100
1u
Mjaybrod
Last 30d: 61-43-1 (+17.1u)
Under 43.5-110
0.91u
Degen’s sleepytime tea
YBK Picks.com
Last 30d: 5-3-0 (+4.5u)
MIZ +5.5-105
3u
Stuck 🚨
Last 30d: 55-54-2 (+0.8u)
OU -5.5-110
0.05u
Can try for small middle with low total. 6.5/7 probably right here especially with Pribula uncertainty
Picks Office
Last 30d: 179-152-3 (+15.3u)
MIZ +6.5-105
1u
Link in Bio for early access
The Pick Don
Last 30d: 9-7-0 (+0.6u)
MIZ +5.5-105
1.05u
Duck
Last 30d: 86-88-0 (-4.1u)
MIZ u17.5-125
0.53u
Big Bets On Campus (CFB)
Last 30d: 0-0-0 (+0.0u)
MIZ +7.5-105
1u
Agree Board @Stuckey2 @_Collin1 https://myaction.app/froqdThRtYb
Doug Ziefel
Last 30d: 146-167-1 (-12.0u)
A.Hardy u115.5 Rush Yds-115
0.5u
D.Burks u42.5 Rec Yds-115
0.5u
Stuck 🚨
Last 30d: 55-54-2 (+0.8u)
MIZ +8-110
0.3u
From podcast. Out in a bit!
Collin Wilson
Last 30d: 0-0-0 (+0.0u)
MIZ +7.5-112
1.12u
As discussed on BBOC
Over 41-120
1.2u
Buying half point to key 41; OU outside top 50 in PFF tackling and broken tackles allowed. Missouri 95th defensive finishing drives
Babs .
Last 30d: 31-27-0 (+2.2u)
MIZ +9.5-110
1u
Mike McNamara
Last 30d: 86-88-0 (+3.6u)
MIZ +9.5-110
0.5u
Missouri vs. Oklahoma Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Missouri vs. Oklahoma Public Betting Percentages
Betting Trends
- Oklahoma are 4-1 in their last 5 games.
- Oklahoma are 4-1 in their last 5 games against the spread
- Oklahoma are 4-0 in their road games against the spread
- The totals have gone OVER in 1 of Oklahoma' last 5 games
- The totals have gone OVER in 1 of Oklahoma' 7 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Team Stats
301
Total Yards
276
71
Total Plays
62
4.23943661971831
Yards Per Play
4.451612903225806
231
YDS
173
20/36
Comps/Atts
14/30
6.416666666666667
YPA
5.766666666666667
0/2
TDs/INTs
2/0
4/20
Sacks/Yards
2/14
Missouri vs. Oklahoma Odds Comparison
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Missouri at Oklahoma Team Totals
MatchupOverUnder | ||
|---|---|---|
Missouri 8-5 | N/A | N/A |
Oklahoma 10-3 | N/A | N/A |





