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Oregon vs. USC Odds & Betting Predictions - September 26, 2026

Oregon at USC

11:30 pm • NBC

Oregon Ducks

5-3
41
41 - 27

USC Trojans

7-2
27

Oregon at USC Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Oregon
5-3
-5.5
-3.5-110
o60.5-110
-180
USC
7-2
u58.5
+3.5-110
u60.5-110
+150
location pinSaturday 11:30 p.m.
September 26, 2026
Los Angeles Memorial ColiseumLos Angeles
Oregon vs. USC Expert Picks
YBK Picks.com
Last 30d: 45-37-3 (+17.0u)
ORE -3.5-105
1.9u
Vegas Refund
Vegas Refund
Last 30d: 31-34-0 (-6.4u)
USC +3.5-110
1.1u
Collin Wilson
Collin Wilson
Last 30d: 86-56-2 (+15.7u)
ORE -122
1u
Project Oregon -5; USC has zero pass defense or pass rush, good for an Oregon OL that is 130th in pass blocking. Ducks D elite against the pass so far, T15 success rate coverage and EPA allowed
Mike McNamara
Mike McNamara
Last 30d: 80-58-1 (+10.2u)
USC +3-110
0.5u
Tyler Shoemaker
Tyler Shoemaker
Last 30d: 3-2-0 (+0.8u)
Under 62.5-110
1.1u
Doug Ziefel
Doug Ziefel
Last 30d: 403-339-10 (+44.4u)
M.Bowman u37.5 Rec Yds-114
0.57u
ORE -2.5-115
0.5u
Ryan Minion
Ryan Minion
Last 30d: 238-251-8 (+0.4u)
Over 61.5-110
$1.00
https://discord.gg/cP6X2bgkS
ORE -2.5-125
$1.00
https://discord.gg/UJjQwM5Er 🦆
Kyle Murray
Kyle Murray
Last 30d: 130-143-6 (+1.5u)
Over 61.5-110
1u
Dan Gaspar
Dan Gaspar
Last 30d: 54-35-9 (+15.6u)
D.Hill o11.5 Rush Att+100
1u
Big Bets On Campus (CFB)
Big Bets On Campus (CFB)
Last 30d: 44-45-3 (-2.3u)
ORE -3-110
0.91u
@_Collin1 https://podcasts.apple.com/us/podcast/college-football-betting-preview-week-4/id1579379256?i=1000791550178
Brandon Kravitz
Brandon Kravitz
Last 30d: 56-69-2 (-6.3u)
USC +138 (Live)
1u
RoyalsProps
RoyalsProps
Last 30d: 40-57-5 (-23.9u)
USC +3.5-115
1.15u
Topper
Topper
Last 30d: 109-96-3 (-14.8u)
USC +3.5-110
1u
Home Undefeated Dog With Same or Better Record Overall: 140-87-6,62% (ROI:19%) Season:2-2-0,50% (ROI:-4%) #TSA
Mjaybrod
Mjaybrod
Last 30d: 58-76-0 (-20.9u)
USC +112 (Live)
1u
Adam Kaufman
Adam Kaufman
Last 30d: 336-307-16 (-15.9u)
ORE -3.5+100
1u
Alex Hinton
Alex Hinton
Last 30d: 107-114-0 (+8.7u)
Over 62.5-110
0.91u
Nick Griffith
Last 30d: 52-59-0 (-3.8u)
USC +3.5-110
1.1u
Scott Rickenbach
Scott Rickenbach
Last 30d: 96-88-2 (-2.1u)
ORE -170
0.59u
Babs .
Babs .
Last 30d: 30-24-1 (+3.1u)
ORE -150
0.89u

Oregon vs. USC Previews & Analysis

  • Oregon vs. USC: Ducks Back in Big Ten Picture? article feature image

    Oregon vs. USC: Ducks Back in Big Ten Picture?

    Collin Wilson•
    Sep 26, 2026 UTC
  • Wilson's NCAAF Week 4 Betting Card article feature image

    Wilson's NCAAF Week 4 Betting Card

    Collin Wilson•
    Sep 26, 2026 UTC
  • Your Week 4 NCAAF Betting Cheat Sheet article feature image

    Your Week 4 NCAAF Betting Cheat Sheet

    Pete Ruden•
    Sep 26, 2026 UTC
  • Our Top 3 NCAAF Player Props for Saturday article feature image

    Our Top 3 NCAAF Player Props for Saturday

    Doug Ziefel•
    Sep 26, 2026 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Oregon vs. USC Public Betting Percentages

Away Logo

Oregon

Public

Home Logo

USC

56%

Bets%

44%

Money%

NCAAF Public Betting Right Arrow

Betting Trends

  • USC are 4-1 in their last 5 games.
  • USC are 3-2 in their last 5 games against the spread
  • USC are 1-2 in their road games against the spread
  • The totals have gone OVER in 1 of USC' last 5 games
  • The totals have gone OVER in 3 of USC' 6 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
USC		3-62-41-21-41-1
Oregon		3-52-31-22-5N/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
USC		4-53-31-22-31-1
Oregon		5-33-22-14-3N/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
USC		7-2N/AN/A4-11-1
Oregon		5-3N/AN/A4-3N/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 19th@RUTW 42-35-21.5 LO 59.5USC -2100
Sep 13thULW 48-30-30.5 LO 58.5USC -6500
Sep 5thFRESW 39-0-22.5 WU 51.5USC -2800
Aug 29thSJSUW 42-26-38.5 LO 61.5-
Dec 31st@TCUL 27-30-4.5 LO 56.5TCU -196
Team Stats

Total

504
Total Yards
446
68
Total Plays
75
7.411764705882353
Yards Per Play
5.946666666666666

Passing

366
YDS
326
27/35
Comps/Atts
23/42
10.457142857142857
YPA
7.761904761904762
2/0
TDs/INTs
2/1
0/0
Sacks/Yards
2/10

Rushing

138
Rush Yards
120
33
Attempts
33
4.181818181818182
YPC
3.6363636363636362
3
TDs
1

Turnovers

0
Fumbles Lost
0
0
Interceptions
1

Efficiency

6/6 100%
Redzone
3/4 75%
6/12 0%
3rd Down
2/11 0%
2/2 0%
4th Down
4/5 0%

First Downs

23
Total
26
13
Pass
17
6
Rush
8
4
Penalty
1

Misc

5/50
Penalties/Yards
6/44

Oregon vs. USC Odds Comparison

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See more NCAAF Odds Right Arrow

Oregon at USC Team Totals

MatchupOverUnder
Oregon
5-3
N/A
N/A
USC
7-2
N/A
N/A