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Kentucky vs. Louisville Odds & Betting Predictions - November 29, 2025

Kentucky at Louisville

5:00 pm • ACC Network

Kentucky Wildcats

7-1
0
0 - 41

Louisville Cardinals

4-3
41

Kentucky at Louisville Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Kentucky
7-1
+6.5
-1-105
o45.5-110
N/A
Louisville
4-3
+1-115
u45.5-112
N/A
location pinSaturday 5:00 p.m.
November 29, 2025
L&N Federal Credit Union StadiumLouisville
Kentucky vs. Louisville Expert Picks
Mike McNamara
Mike McNamara
Last 30d: 68-56-2 (+3.8u)
UK +130
0.3u
Sean Zerillo
Sean Zerillo
Last 30d: 121-113-6 (+6.3u)
UK +100
0.25u
Kody Malstrom
Kody Malstrom
Last 30d: 61-48-1 (+3.3u)
LOU -2.5-116
0.5u
Jeremiah Rose
Jeremiah Rose
Last 30d: 47-55-3 (-1.3u)
LOU -118
0.42u
Boyd / FanDuel
Picks Office
Picks Office
Last 30d: 0-0-0 (+0.0u)
UK +3-115
1u
Link in bio for early access
The Degenerates
The Degenerates
Last 30d: 62-59-1 (-1.8u)
UK +3 (Live)-110
1.1u
Brian Bitler
Brian Bitler
Last 30d: 72-75-4 (-3.3u)
UK +2.5-109
3u
Road to CFB
Road to CFB
Last 30d: 32-20-0 (+9.5u)
UK +3-112
1.12u
Babs .
Babs .
Last 30d: 36-32-1 (-2.6u)
UK +3-125
1u

Kentucky vs. Louisville Previews & Analysis

  • Your Week 14 NCAAF Betting Cheat Sheet article feature image

    Your Week 14 NCAAF Betting Cheat Sheet

    Pete Ruden•
    Nov 29, 2025 UTC
  • Kentucky vs Louisville: Spot to Target in the Governor’s Cup article feature image

    Kentucky vs Louisville: Spot to Target in the Governor’s Cup

    Road ToCFB•
    Nov 29, 2025 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Kentucky vs. Louisville Public Betting Percentages

Away Logo

Kentucky

Public

Home Logo

Louisville

59%

Bets%

41%

Money%

NCAAF Public Betting Right Arrow

Betting Trends

  • Louisville are 2-3 in their last 5 games.
  • Louisville are 2-3 in their last 5 games against the spread
  • Louisville are 0-2 in their road games against the spread
  • The totals have gone OVER in 4 of Louisville' last 5 games
  • The totals have gone OVER in 3 of Louisville' 4 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Louisville		4-33-10-23-31-0
Kentucky		7-14-13-03-04-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Louisville		6-13-12-05-11-0
Kentucky		5-33-22-11-24-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Louisville		4-3N/AN/A4-20-1
Kentucky		7-1N/AN/A3-04-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 22nd@SMUL 6-38+3.5 LU 49.5SMU +154
Nov 15thCLEML 19-20-1.5 LU 51CLEM -125
Nov 9thCALL 26-29-18.5 LO 48.5CAL -1100
Nov 1st@VTW 28-16-10.5 WU 52.5LOU -395
Oct 25thBCW 38-24-25.5 LO 54.5LOU -2800
Team Stats

Total

140
Total Yards
440
52
Total Plays
71
2.6923076923076925
Yards Per Play
6.197183098591549

Passing

100
YDS
182
13/26
Comps/Atts
12/21
3.8461538461538463
YPA
8.666666666666666
0/2
TDs/INTs
3/0
6/48
Sacks/Yards
1/6

Rushing

40
Rush Yards
258
26
Attempts
50
1.5384615384615385
YPC
5.16
0
TDs
2

Turnovers

0
Fumbles Lost
0
2
Interceptions
0

Efficiency

0/0 0%
Redzone
6/6 100%
2/13 0%
3rd Down
4/12 0%
0/1 0%
4th Down
2/2 0%

First Downs

10
Total
26
4
Pass
8
4
Rush
17
2
Penalty
1

Misc

6/54
Penalties/Yards
9/75

Kentucky vs. Louisville Odds Comparison

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Kentucky at Louisville Team Totals

MatchupOverUnder
Kentucky
7-1
N/A
N/A
Louisville
4-3
N/A
N/A