4 Best Predictions, Picks for College Football Saturday: Smartest Bets Include Iowa State vs. Oklahoma, Nebraska vs. Wisconsin

4 Best Predictions, Picks for College Football Saturday: Smartest Bets Include Iowa State vs. Oklahoma, Nebraska vs. Wisconsin article feature image
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Photo by Steven Branscombe/Getty Images. Pictured: Head coach Scott Frost of the Nebraska Cornhuskers

The college football Week 12 slate has everything we want as bettors, including early games, late games, big games and low-profile games all offering value.

This doesn’t mean that our betting tools are suggesting to make more college football wagers than on a typical  Saturday, but that the smartest sides and totals come from games that will be both public and under-the-radar matchups.

With the help of The Action Network’s PRO Report value indicators, let’s detail Saturday’s four smartest college football bets.

College Football Picks & Predictions

*Odds and betting data as of Friday afternoon

Iowa State vs. Oklahoma Betting Pick

12 p.m. ET | FOX

Iowa State vs. Oklahoma is about as clear-cut as it gets for one-sided, sharp betting action.

This spread opened at Cyclones +5.5 at PointsBet and behind multiple waves of sharp betting has been driven down to a consensus spread of +3.5.

In addition, Iowa State has attracted just 40% of the tickets, but 68% of the money wagered on this spread, showing that big bettors taking the points has forced oddsmakers to adjust this line.

And while the current consensus spread is +3.5, BetMGM is still hanging +4 as of the time of writing, so be sure to snag that number if you plan on tailing the wiseguys in this matchup.

PRO Report Pick: Iowa State +4

Nebraska vs. Wisconsin Betting Pick

3:30 p.m. ET | ABC

Not only are the pros getting down on Nebraska vs. Wisconsin, but two separate historically-profitable betting systems are also aligned with the sharp side of this game.

The latest Nebraska vs. Wisconsin spread sits between Badgers -8.5 and -9, but as I just mentioned, smart money has already shaped this number.