The Louisiana Ragin' Cajuns take on the South Alabama Jaguars in Mobile, Alabama. Kickoff is set for 3:30 p.m. EDT on ESPN+.
South Alabama is favored by 4 points on the spread with a moneyline of -185. The total is set at 54 points.
Here’s my Louisiana vs. South Alabama prediction and college football picks for Saturday, November 1, 2025.
Louisiana vs South Alabama Prediction
- Louisiana vs. South Alabama Pick: Louisiana +4 (-110, bet365)
My South Alabama vs. Louisiana best bet is on the Ragin' Cajuns. Find the best line available on our live NCAAF odds page.
Louisiana vs South Alabama Odds
| Louisiana Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+4 -110 | 54 -110o / -110u | +155 |
| South Alabama Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-4 -110 | 54 -110o / -110u | -185 |
- Louisiana vs South Alabama point spread: South Alabama -4 (-110), Louisiana +4 (-110)
- Louisiana vs South Alabama over/under: 54 (-110o / -110u)
- Louisiana vs South Alabama moneyline: Louisiana +155, South Alabama -185
Louisiana vs South Alabama Pick
This game triggered one of our Action PRO betting systems, powered by Evan Abrams.
Small Dog in Small Game is a college football system built around the idea that underdogs in lower-profile matchups can be undervalued when attention and betting volume are limited.
These games typically kick off in the afternoon or evening window and occur early in the season, within the first nine contests, when teams are still developing identities. The underdog in this range is small to moderate, with spreads between 2 and 11.5 points, and often comes into the game with little momentum, having won or lost only a game or two in a short streak.
Because betting activity on these contests is lower than the daily average, the market is less efficient, and lines move very little from open to close, creating opportunities in which perception has more influence than actual performance.
When public money leans toward the favorite but not overwhelmingly, the small dog benefits from value created by these market dynamics and covers more often than expected.
Pick: Louisiana +4 (-110, bet365)
