The Missouri Tigers take on the Arkansas Razorbacks in Fayetteville, Arkansas. Kickoff is set for 3:30 p.m. EST on SEC Network.
Missouri is favored by 2.5 points on the spread with a moneyline of -150. The total is set at 55 points.
Here’s my Missouri vs. Arkansas predictions and college football picks for Saturday, November 29, 2025.
Missouri vs Arkansas Prediction
- Missouri vs. Arkansas Pick: Arkansas +3 or Better
My Arkansas vs. Missouri best bet is on the Razorbacks to cover the spread. Find the best line available on our live NCAAF odds page.
Missouri vs Arkansas Odds
| Missouri Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-2.5 -115 | 55 -110o / -110u | -150 |
| Arkansas Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+2.5 -105 | 55 -110o / -110u | +125 |
- Missouri vs Arkansas point spread: Missouri -2.5
- Missouri vs Arkansas over/under: 55
- Missouri vs Arkansas moneyline: Missouri -150, Arkansas +125
Missouri vs Arkansas Preview
Missouri Tigers Betting Preview: Does Beau Know Best?
It felt like the Week 7 loss to Alabama spelled the beginning of the end for the Tigers. Since then, they have gone 2-3.
Perhaps it’s no fault of their own, as starting quarterback Beau Pribula went down in the middle of Week 9’s loss to Vanderbilt, forcing coach Eli Drinkwitz to turn to Matt Zollers.
Zollers was hardly impressive, and luckily, Pribula returned last week against Oklahoma, but by then it was too late. Pribula completed 55% of his passes with no touchdowns and two picks.
For the most part, though, this team is carried by Ahmad Hardy, the transfer running back out of UL-Monroe, who has taken the SEC by storm. Currently, he leads the conference in rushing yards with 1,403 as well as 6.6 yards per carry. He has also scored 15 times.
Mizzou’s strong run game is going to play perfectly into this game because Arkansas is a terrible run-stopping team. The Razorbacks rank 127th nationally in Rush Success Rate allowed.
Not only that, the Hogs allow 184 rushing yards per game, which ranks 110th in the FBS.
On the defensive end, there are several difference makers such as Zion Young, Josiah Trotter and Toriano Pride. Mizzou also ranks 11th in Success Rate allowed versus Arkansas’ 13th-ranked offense.
Arkansas Razorbacks Betting Preview: Ground and Pound
There has been a whole lot of speculation regarding the head coaching position at Arkansas. There are rumors circulating that USF coach Alex Golesh will be the Razorbacks' new coach.
While there’s no confirmation, there’s definitely a whole lot of intrigue surrounding it.
For now, Bobby Petrino will continue to coach the program. Either way, it’s going to look a whole lot different in Fayetteville next season.
Taylen Green has done an excellent job given the circumstances. Currently, with a lower-tiered offensive line, Green has been completing passes at a 61% clip with a strong touchdown-to-interception ratio. He’s also been a menace on the ground, rushing for over 770 yards and just under six yards per carry.
But aside from that, Mike Washington has been a bright spot on the ground, rushing for a career high 1,020 yards and 6.5 yards per carry.
Combined, the two of them have combined to rank fourth in Rush Success Rate, which should be an interesting battle with Mizzou, which rank 12th in Rush Success Rate allowed, and 14th in the nation in rushing yards allowed per game.
Defensively, with nine losses, there’s no surprise that this program is at the bottom of the barrel. The Razorbacks rank 125th in Success Rate allowed while allowing the ninth-most points per game.
Missouri vs Arkansas Pick, Betting Analysis
Everything you’ve seen from Arkansas, you can throw it out the window.
In its past three games, the Razorbacks have lost by three to Mississippi State, lost by one to LSU, and then hung around with 17th-ranked Texas until the Longhorns pulled away in the second half.
Meanwhile, Mizzou, while already bowl-eligible, is on the downswing.
Perhaps Pribula comes back and slices up Arkansas’s defense, and I wouldn’t be surprised to see Hardy go off for over 100 yards again.
The problem is, this game is being played in Fayetteville, and Mizzou doesn’t have much experience on the road. And when it does, it squanders.
In three road games played this season, the Tigers are 1-2, losing 17-10 to Vanderbilt and, more recently, 23-6 against Oklahoma.
Arkansas is nowhere near those two teams, but given how it’s been strong in its past three games, I think the Razorbacks have a solid chance to play their best football on Saturday.
Pick: Arkansas +3 or Better
Missouri vs Arkansas Betting Trends
