The Troy Trojans take on the Southern Miss Golden Eagles in Hattiesburg, Mississippi. Kickoff is set for 3:30 p.m. EST on ESPN+.
Southern Miss is favored by -6.5 points on the spread with a moneyline of -250. The total is set at 50.5 points.
Here’s my Troy vs. Southern Miss prediction and college football picks for Saturday, November 29, 2025.
Troy vs Southern Miss Prediction
- Troy vs. Southern Miss Pick: Troy +6.5
My Southern Miss vs. Troy best bet is on the Trojans to cover. Find the best line available on our live NCAAF odds page.
Troy vs Southern Miss Odds
| Troy Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+6.5 -110 | 50.5 -110o / -110u | +200 |
| Southern Miss Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-6.5 -110 | 50.5 -110o / -110u | -245 |
- Troy vs Southern Miss point spread: Southern Miss -6.5 (-110), Troy +6.5 (-110)
- Troy vs Southern Miss over/under: 50.5 (-110o / -110u)
- Troy vs Southern Miss moneyline: Troy +200, Southern Miss -245
Troy vs Southern Miss Preview
This game triggered one of our Action PRO betting systems, powered by Evan Abrams.
In both regular season and postseason college football, home favorites in conference play who have performed poorly against the spread in recent games are often overvalued.
A string of ATS losses signals that market expectations have consistently outpaced on-field results, yet public perception and home-field bias can still inflate the line.
Conference opponents, familiar with schemes and tendencies, are well-positioned to exploit these weaknesses.
This creates an environment where fading the struggling home favorite offers consistent value.
You may be tempted to back Braylon Braxton and the Golden Eagles, who hold a 5-2 Sun Belt record and can clinch the Sun Belt championship game with a win on Saturday.
But Troy is also 5-2 in league play and can do the same.
But Southern Miss hasn't been playing as well recently, losing back-to-back games against South Alabama and Texas State — the latter by a disgusting 41-14 score.
Troy has had its struggles this season, but it pieced together a solid 31-19 win over Georgia State last week behind a strong performance from quarterback Goose Crowder (27-for-43, 340 yards, 4 TDs, 0 INTs).
Teams that fit the system this season are 14-7-2 ATS, a 67% win rate generating a 25% ROI.
Pick: Troy +6.5
