The Washington State Cougars take on the Ole Miss Rebels in Oxford, MS. Kickoff is set for 12:45 p.m. ET on SEC Network.
Ole Miss is favored by -32.5 points on the spread, and the total is set at 58.5 points.
Here’s my Washington State vs. Ole Miss predictions and college football picks for Saturday, October 11, 2025.


Washington St vs Ole Miss Prediction
- Washington State vs. Ole Miss Pick: Over 58.5
My Ole Miss vs. Washington State best bet is on the over. Find the best line available on our live NCAAF odds page.
Washington State vs Ole Miss Odds
Washington State Odds | ||
---|---|---|
Spread | Total | Moneyline |
+32.5 -110 | 58.5 -110o / -110u | N/A |
Ole Miss Odds | ||
---|---|---|
Spread | Total | Moneyline |
-32.5 -110 | 58.5 -110o / -110u | N/A |
- Washington State vs Ole Miss point spread: Ole Miss -32.5
- Washington State vs Ole Miss over/under: 58.5 points

Washington State vs Ole Miss Pick, Betting Analysis
Washington State allowed 59 points to both North Texas and Washington already this season, and now it has to face Trinidad Chambliss and No. 4 Ole Miss on the road.
This could be a disaster waiting to happen for the Cougars, but instead of backing the Rebels to cover such a large spread, the play is on the total to go over.
Evan Abrams' "Unfamiliar Blowout Overs, No Wind" system backs this play, which gives us nice value considering the system has a return on investment of 17% since its inception.
"Unfamiliar Blowout Overs, No Wind" is a college football system that identifies high scoring potential in non-conference games where large mismatches and calm weather create ideal conditions for offense.
During the regular season, when the home team is favored by more than 30 points, the talent gap often produces quick scoring opportunities and little resistance from the underdog.
The lack of conference familiarity further benefits the stronger team, as defensive preparation is weaker and big plays become more likely.
With the closing total set below 60, the market isn't fully pricing in the offensive potential of these lopsided matchups.
Calm conditions with wind speeds under 10 miles per hour remove one of the biggest obstacles to scoring, making passing and kicking more efficient.
These factors combine to create a profile where the over consistently cashes as favorites pile on points and weaker opponents contribute through late scoring once the game is out of reach.
Pick: Over 58.5