Panthers vs. Jaguars Odds & Betting Predictions - September 7, 2025

Panthers at Jaguars

5:00 pm • FOX
10 - 26

Panthers at Jaguars Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Panthers
0-1
+2.5
+4.5-115
o45.5-110
+184
Jaguars
1-0
u46.5
-4.5-110
u45.5-110
-220
location pinSunday 5:00 p.m.
September 07, 2025
EverBank StadiumJacksonville
Panthers vs. Jaguars Expert Picks
Shady Biev
Shady Biev
Last 30d: 23-29-0 (-6.9u)
CAR o13 Team Total (Live)-115
2.3u
Ryan Sura
Ryan Sura
Last 30d: 51-59-5 (-8.8u)
Over 45.5 (Live)-112
1.12u
Jeremiah Rose
Jeremiah Rose
Last 30d: 22-19-3 (+2.3u)
Under 46.5-110
0.23u
Wynn LV
Ryan Sura
Ryan Sura
Last 30d: 51-59-5 (-8.8u)
C.Hubbard Anytime TD Scorer Yes+137
1.1u
FD Profit Boost
B.Strange Anytime TD Scorer Yes+400
0.4u
Kyle Murray
Kyle Murray
Last 30d: 43-52-3 (-3.2u)
J.Sanders o2.5 Recs-104
1.04u
Picks Office
Picks Office
Last 30d: 78-77-5 (-2.4u)
JAC -3-115
0.87u
Capper Central
Capper Central
Last 30d: 95-71-1 (+11.8u)
CAR +4.5-112
0.84u
YBK Picks.com
Last 30d: 21-32-0 (-30.4u)
JAC -4.5-105
1.9u
Ryan Sura
Ryan Sura
Last 30d: 51-59-5 (-8.8u)
CAR +4.5-115
1.15u
Brandon Anderson
Brandon Anderson
Last 30d: 6-18-0 (-2.6u)
CAR +4.5-110
0.25u
I just don’t understand this line at all. We are sure Jacksonville is good suddenly? I’m optimistic about this coaching staff long-term too, but this is one of the youngest greenest staffs I’ve seen and change doesn’t come overnight. Everyone way too confident in a Jaguars team that’s never been good with any version of Trevor Lawrence yet. Lawrence also struggles outdoors especially in the rain and the weather looks nasty today, and Carolina‘s best strength is running the football while Jacksonville has had no run game for years. There’s no reason Carolina should be this much of an underdog against a team that might be just as good as, and honestly they might just win out right.
CAR +180
0.25u
I just don’t understand this line at all. We are sure Jacksonville is good suddenly? I’m optimistic about this coaching staff long-term too, but this is one of the youngest greenest staffs I’ve seen and change doesn’t come overnight. Everyone way too confident in a Jaguars team that’s never been good with any version of Trevor Lawrence yet. Lawrence also struggles outdoors especially in the rain and the weather looks nasty today, and Carolina‘s best strength is running the football while Jacksonville has had no run game for years. There’s no reason Carolina should be this much of an underdog against a team that might be just as good as, and honestly they might just win out right.
Sandy Plashkes
Sandy Plashkes
Last 30d: 51-69-2 (-18.7u)
T.Hunter o48.5 Rec Yds-118
1.18u
Brian Bitler
Brian Bitler
Last 30d: 97-81-0 (+39.0u)
CAR +4-110
3u
Over 46.5-105
3u
Chris Raybon
Chris Raybon
Last 30d: 7-6-0 (-0.4u)
JAC -3.5-110
0.91u
#SundaySixPack
Will Brinson
Will Brinson
Last 30d: 18-18-0 (+3.0u)
JAC -3.5-109
1u
Moneyline Hacks
Moneyline Hacks
Last 30d: 98-89-6 (+19.0u)
T.Hunter o0.5 Rush Yds+350
0.5u
🚨Yesterday was a good overall day for VIP. Cashing the 3 unit POD! 🤑⬇️ 🔥Dak Prescott (Cowboys) under 7.5 Rush Yds (-110) 3 units✅ We gave out free NFL player props in our Discord ⬇️ https://discord.gg/A8v49URQaG Crushing it year after year. 📈
Sean Koerner
Sean Koerner
Last 30d: 11-23-1 (-4.3u)
T.Bigsby o10.5 Longest Rush-112
0.56u
Liam Coen’s scheme should give a boost to Jacksonville’s backfield, but usage is still unsettled between Travis Etienne, Tank Bigsby, and rookie Bhayshul Tuten. Early signs point to Etienne and Bigsby handling most of the work out of the gate, with Tuten eased in initially. Bigsby projects to handle early-down snaps, which makes his longest rush prop more appealing than trying to pin down volume. The Jaguars are 3.5-point favorites, implying they’ll play with a lead at a ~17% higher rate than last year, which sets up a higher team run rate overall. Even if Bigsby’s touches are capped, it only takes one carry for him to clear this number. The matchup also helps. Carolina’s run defense has been among the league’s worst over the last two seasons, and while healthier and bolstered with new pieces, this is still one of the easiest spots Bigsby will face all year. Carolina allowed 2.09 yards before contact per rush (2nd-highest) last season. That’s dangerous against a runner like Bigsby, who consistently generates after contact as he ranked 3rd in yards after contact per attempt last year. With the setup of better run-blocking lanes plus Bigsby’s ability to turn contact into chunk gains, the conditions are strong for at least one explosive run. I project his median longest rush closer to 13 yards with about a 59% chance of clearing 10.5.
Roger Goodell
Roger Goodell
Last 30d: 8-9-0 (-1.5u)
CAR +3.5-105
1u
CAR +160
0.5u
Grant Neiffer
Grant Neiffer
Last 30d: 46-120-9 (+38.6u)
B.Thomas Anytime TD Scorer Yes+130
0.65u
Action Pod NFL Picks
Action Pod NFL Picks
Last 30d: 8-17-0 (-5.1u)
T.Lawrence Anytime TD Scorer Yes+425
1u
@ChrisRaybon Favorite ATD https://myaction.app/naCzRpNcoWb
JAC -3.5+100
1u
@sundaysixpack @ChrisRaybon https://myaction.app/naCzRpNcoWb
Firefighter Bets
Firefighter Bets
Last 30d: 110-101-0 (+2.9u)
C.Rozeboom o7.5 Tackles + Ast-135
0.74u
Sunday Six Pack
Sunday Six Pack
Last 30d: 4-2-0 (+1.8u)
JAC -3.5+100
1u
Stuck 🚨
Stuck 🚨
Last 30d: 26-23-1 (-0.4u)
T.Lawrence Anytime TD Scorer Yes+430
0.15u
Chris Raybon
Chris Raybon
Last 30d: 7-6-0 (-0.4u)
T.Lawrence Anytime TD Scorer Yes+430
1u
Coen hinted JAX may use tush push
Firefighter Bets
Firefighter Bets
Last 30d: 110-101-0 (+2.9u)
J.Sanders o19.5 Rec Yds-115
0.87u
B.Strange o28.5 Rec Yds-115
0.87u
Chris Gimino
Chris Gimino
Last 30d: 11-8-0 (+4.9u)
T.Etienne o13.5 Rec Yds-110
1u
T.Etienne u9.5 Rush Att-108
1u
Kyle Murray
Kyle Murray
Last 30d: 43-52-3 (-3.2u)
J.Sanders o20.5 Rec Yds-110
1u
FTN Fantasy
FTN Fantasy
Last 30d: 60-104-0 (-47.1u)
CAR +3-112
1u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 110-124-2 (-18.6u)
CAR +2.5+100
1u
Overall: 70-33-3,68% (ROI:31%)
Chris Raybon
Chris Raybon
Last 30d: 7-6-0 (-0.4u)
JAC o23.5 Team Total-130
0.77u

Panthers vs. Jaguars Previews & Analysis

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Panthers vs. Jaguars Props

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Prop Odds Comparison

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Line Movement Tracker

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Panthers vs. Jaguars Public Betting Percentages

Away Logo

Panthers

Public

54%

Bets%

46%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Jaguars
1-01-0N/A1-0N/A
Panthers
0-1N/A0-1N/A0-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Jaguars
0-10-1N/A0-1N/A
Panthers
0-1N/A0-1N/A0-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Jaguars
1-0N/AN/A1-0N/A
Panthers
0-1N/AN/AN/A0-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Aug 23rd@MIAL 6-14+7 LU 39.5MIA +240
Aug 17th@NOL 17-17-2.5 LU 40.5NO -132
Aug 9thPITL 25-31-6 LO 38.5PIT -241
Jan 5th@INDL 23-26+3.5 WO 46.5IND +155
Dec 29thTENW 20-13+1 WU 38.5JAC -105

Jaguars vs. Panthers Injury Updates

Jaguars Injuries

  • Cole Van Lanen
    OL

    Van Lanen is questionable with shoulder

    Questionable

  • Montaric Brown
    CB

    Brown is out with ankle

    Out

  • Wyatt Milum
    OL

    Milum is out with knee

    Out

Panthers Injuries

  • Ikem Ekwonu
    T

    Ekwonu is doubtful with illness

    Doubtful

  • Damarri Mathis
    CB

    Mathis is out with knee

    Out

  • Jalen Coker
    WR

    Coker is out with quad

    Out

Team Stats
255
Total Yards
378
61
Total Plays
63
4.2
Yards Per Play
6
154
YDS
178
18/35
Comps/Atts
19/31
3.944
YPA
5.742
1/2
TDs/INTs
1/1
1/12
Sacks/Yards
0/0
113
Rush Yards
200
25
Attempts
32
4.52
YPC
6.25
0
TDs
1
1
Fumbles Lost
0
2
Interceptions
1

Efficiency

0/1 0%
Redzone
2/5 40%
8/15 0%
3rd Down
5/12 0%
0/2 0%
4th Down
2/2 0%

First Downs

15
Total
19
8
Pass
9
5
Rush
10
2
Penalty
0
4/35
Penalties/Yards
11/93
29:00
Possession
31:00

Panthers vs. Jaguars Odds Comparison

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Panthers at Jaguars Team Totals

MatchupOverUnder
Panthers
0-1
o20.5-113
u20.5-115
Jaguars
1-0
o26-111
u26-116