Dolphins vs. 49ers Odds & Betting Predictions - September 20, 2026

Dolphins at 49ers

8:25 pm • FOX
13 - 35

Dolphins at 49ers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Dolphins
0-2
+10.5
+12.5-110
o45-108
+700
49ers
2-0
u46.5
-13-107
u45-110
-1000
location pinSunday 8:25 p.m.
September 20, 2026
Levi's StadiumSanta Clara
Dolphins vs. 49ers Expert Picks
John Feltman
John Feltman
Last 30d: 59-51-0 (+0.6u)
SF -14.5 (Live)-120
1u
💰🦡 Jake
💰🦡 Jake
Last 30d: 32-41-0 (-9.2u)
MIA +7.5 (1H)-115
1.15u
Kyle Murray
Kyle Murray
Last 30d: 105-102-4 (+0.9u)
D.Samuel o3.5 Recs+126
0.79u
M.Washington o3.5 Recs+108
1u
B.Purdy o28.5 Pass Att-110
1.1u
Mjaybrod
Mjaybrod
Last 30d: 47-43-1 (+3.9u)
Over 45+103
1.03u
Sandy Plashkes
Sandy Plashkes
Last 30d: 75-57-1 (+32.8u)
MIA +13.5-120
1.2u
Derek Carty
Derek Carty
Last 30d: 30-54-5 (-5.1u)
W.Kacmarek Anytime TD Scorer Yes+2232
0.25u
There is a value opportunity on Will Kacmarek's touchdowns prop. THE BLITZ is projecting 0.06 touchdowns for him with a 7% chance that he exceeds 0.5 touchdowns. If you can get the over at +2232 or better, there is some great value here. This play is good down to at least +1534. Love THE BLITZ? Get all of Carty’s sports betting projections at EV Analytics: https://evanalytics.com/products/nfl-premium-subscription?ref=zdlkmgz
Allan Lem
Allan Lem
Last 30d: 36-24-0 (+4.6u)
Z.Sieler u3.5 Tackles + Ast-129
0.5u
Tailing @The_Oddsmaker
Sean Koerner🔮
Sean Koerner🔮
Last 30d: 19-23-0 (-2.0u)
Z.Sieler u3.5 Tackles + Ast-129
0.5u
Sieler is a really good interior lineman with multiple 10+ sack seasons, but this is another spot where I think the tackle number is just too high. Like I mentioned last week, Brock Purdy is one of the toughest QBs in the league to actually sack, which takes away one of Sieler’s cleaner paths to padding this stat. Miami also faced 37 rush attempts last week and Sieler still finished with only 3 total tackles. I have this number about a full tackle too high and give him roughly a 67% chance to stay under 3.5.
Collin Whitchurch
Collin Whitchurch
Last 30d: 57-62-0 (+5.6u)
C.McCaffrey u40.5 Rec Yds-111
0.28u
Matt DiLeo
Matt DiLeo
Last 30d: 50-25-1 (+15.1u)
D.Robinson o1.5 Recs-134
0.75u
Kyle Murray
Kyle Murray
Last 30d: 105-102-4 (+0.9u)
D.Samuel Anytime TD Scorer Yes+250
1u
Gilles Gallant
Gilles Gallant
Last 30d: 13-23-0 (+7.0u)
D.Samuel Anytime TD Scorer Yes+230
0.5u
Doug Ziefel
Doug Ziefel
Last 30d: 285-332-13 (-0.9u)
C.McCaffrey u45.5 Rec Yds-115
0.5u
Nick Giffen
Nick Giffen
Last 30d: 26-54-0 (+7.8u)
C.McCaffrey u45.5 Rec Yds-115
1u
TAN Pod Touchdown Show
TAN Pod Touchdown Show
Last 30d: 17-43-0 (+1.4u)
Brandon Anderson
Brandon Anderson
Last 30d: 26-37-0 (+12.9u)
MIA +13.5-110
0.75u
I won't even pretend to make a football case for the Dolphins. Miami looked abhorrent last week. This is strictly a numbers, trends, and spot play. The 49ers are returning from a full week in Australia, and we don't truly know how that body clock adjustment is going to affect them. Kyle Shanahan's teams notoriously play with their food and struggle to blow out bad teams. The Niners only covered a 14-point spread four times over the last two seasons. Before Week 1, this line was sitting at 10.5. It has moved three full points based on one week of results. That is an overreaction. Week 2 road 'dogs coming off a double-digit loss hit at an 83% rate. Teams that win by 17+ in Week 1 as underdogs of a touchdown or less (like the 49ers just did) are an ugly 3-15 ATS (17%) in Week 2. I have no idea how we get there—a key Dolphins special teams play, a sloppy tired Niners mistake, maybe a backdoor garbage-time touchdown—I don't care. Just give me the points.
Doug Ziefel
Doug Ziefel
Last 30d: 285-332-13 (-0.9u)
D.Achane o83.5 Rush + Rec Yds-115
0.5u
Grant Neiffer
Grant Neiffer
Last 30d: 26-123-2 (-0.5u)
D.Samuel Anytime TD Scorer Yes+230
0.25u
Adam Kaufman
Adam Kaufman
Last 30d: 133-145-1 (-31.1u)
SF -13-110
1u
Frank Ammirante
Frank Ammirante
Last 30d: 146-159-4 (-11.4u)
C.McCaffrey o14.5 Rush Att-106
1.06u
D.Achane u4.5 Recs-150
1u
Doug Ziefel
Doug Ziefel
Last 30d: 285-332-13 (-0.9u)
B.Purdy u1.5 Pass TDs+170
0.29u
M.Willis u0.5 Int+140
0.5u
Derek Carty
Derek Carty
Last 30d: 30-54-5 (-5.1u)
M.Willis u0.5 Int+140
1.4u
THE BLITZ is forecasting 0.72 interceptions for Malik Willis compared to 0.89 interceptions implied by sportsbooks, so I believe there is some value here. If you take the under, you’d be projected to win 62% of the time, resulting in a 35% ROI. Based on a $100 wager, the expected value here would be $34.92. This play is good down to at least -117. Love THE BLITZ? Get all of Carty’s sports betting projections at EV Analytics: https://evanalytics.com/products/nfl-premium-subscription?ref=zdlkmgz
Doug Ziefel
Doug Ziefel
Last 30d: 285-332-13 (-0.9u)
G.Dulcich o2.5 Recs+135
0.37u
Kody Malstrom
Kody Malstrom
Last 30d: 38-34-1 (+0.2u)
Under 45.5-110
0.55u
RoyalsProps
RoyalsProps
Last 30d: 24-21-1 (-0.3u)
K.Black o37.5 Rush Yds-114
1.14u
Kendra Middleton
Kendra Middleton
Last 30d: 6-12-0 (-2.4u)
MIA +13.5-108
0.25u
OldSchool0909
Last 30d: 93-118-1 (-26.1u)
MIA +13.5-118
1u
Doug Ziefel
Doug Ziefel
Last 30d: 285-332-13 (-0.9u)
Under 46.5-110
0.55u
Frank Ammirante
Frank Ammirante
Last 30d: 146-159-4 (-11.4u)
MIA +13-110
1.1u

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Dolphins vs. 49ers Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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Dolphins vs. 49ers Public Betting Percentages

Away Logo

Dolphins

Public

13%

Bets%

87%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
49ers
2-01-0N/A1-01-0
Dolphins
0-2N/A0-2N/A0-2

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
49ers
1-11-0N/A1-00-1
Dolphins
1-1N/A1-1N/A1-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
49ers
2-0N/AN/A1-01-0
Dolphins
0-2N/AN/AN/A0-2

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 11th@LAW 27-7+3.5 WU 47.5SF +166
Aug 28th@LVW 18-12+3.5 WU 37.5SF +139
Aug 21st@LACW 41-17+2.5 WO 44.5SF +132
Aug 14thTENL 13-19+6.5 WU 40TEN +237
Jan 18th@SEAL 6-41+7 LO 44.5SEA +250

Dolphins vs. 49ers Injury Updates

Dolphins Injuries

  • Jaylen Wright
    RB

    Wright is questionable with neck

    Questionable

  • Caleb Douglas
    WR

    Douglas is questionable with ankle

    Questionable

49ers Injuries

  • Mike Evans
    WR

    Evans is questionable with hip

    Questionable

  • Demarcus Robinson
    WR

    Robinson is out with ankle

    Out

  • Christian Kirk
    WR

    Kirk is out with calf

    Out

  • Jake Tonges
    TE

    Tonges is out with knee

    Out

  • De'Zhaun Stribling
    WR

    Stribling is out with ankle

    Out

Team Stats
284
Total Yards
382
56
Total Plays
49
5.1
Yards Per Play
7.8
197
YDS
287
14/23
Comps/Atts
20/22
6.741
YPA
13.045
1/0
TDs/INTs
2/0
4/15
Sacks/Yards
0/0
102
Rush Yards
95
29
Attempts
27
3.517
YPC
3.519
0
TDs
3

Turnovers

0
Fumbles Lost
0
0
Interceptions
0

Efficiency

0/2 0%
Redzone
5/5 100%
7/15 0%
3rd Down
5/7 0%
1/2 0%
4th Down
0/0 0%

First Downs

13
Total
23
8
Pass
16
4
Rush
6
1
Penalty
1
7/50
Penalties/Yards
7/78
30:13
Possession
29:47

Dolphins vs. 49ers Odds Comparison

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Dolphins at 49ers Team Totals

MatchupOverUnder
Dolphins
0-2
N/A
N/A
49ers
2-0
N/A
N/A