The Los Angeles Chargers (0-6) and Los Angeles Rams (3-4) will face off in NFL Week 8. Kickoff is set for 4:05 p.m. ET from SoFi Stadium in Inglewood, Calif. The game will broadcast live on FOX.
The Rams are 6.5-point favorites over the Chargers on the spread, with the over/under set at 45.5 points. Los Angeles is a -300 moneyline favorite, while Los Angeles is a +245 underdog to pull off the upset.
Let's get into my Chargers vs Rams predictions and NFL picks for the Battle of LA.
- Chargers vs Rams pick: Chargers Moneyline (+245)
My Chargers vs Rams best bet is Los Angeles moneyline (+245), with the best price currently available at FanDuel. Make sure to find the best odds by checking our live NFL odds page.
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Chargers vs Rams Odds
| Chargers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+6.5 -105 | 45.5 -105o / -115u | +245 |
| Rams Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-6.5 -115 | 45.5 -105o / -115u | -300 |
- Chargers vs Rams Moneyline: Chargers +245, Rams -300
- Chargers vs Rams Spread: Chargers +6.5, Rams -6.5
- Chargers vs Rams Total: 45.5
Chargers vs Rams NFL Week 8 Preview
I say this every week but it remains true: the Chargers offense is broken, and they appear to be making no significant changes with the club publicly backing much-maligned offensive coordinator Mike McDaniel.
No one wants to back this team … but this is their kitchen sink game.
Coming out of the bye week, the Chargers are getting significantly healthier on both sides of the ball and expecting reinforcements in the secondary and at the skill positions.
Most importantly, the Chargers defense matches up perfectly against what the Rams want to do. Because of the injury of Davante Adams, the Rams are leaning into big, heavy offensive personnel packages — the Chargers have been one of the best defenses in the entire league at shutting down heavy personnel.
While the Chargers are getting healthy, the Rams are dealing with mounting cluster injuries.
The Rams have already lost multiple pieces on the offensive and defensive lines, and now they are dealing with the loss of Davante Adams. He joins the likes of Poona Ford, Myles Garrett, Terrance Ferguson, and Kobie Turner on injured reserve.
Chargers vs Rams Prediction, Betting Analysis
When you factor in the injury variance trending in the Chargers' favor, the schematic defensive advantages for Los Angeles against heavy sets, and a glaring special teams edge, I think the Chargers are live underdogs to win their first game of the season.
With two weeks to prepare, expect the Chargers to figure out a way to move the ball just enough against a depleted Rams roster.
This is essentially neutral-site game at SoFi Stadium — there will undoubtedly be more Rams fans, but that should be something Chargers players should be accustomed to by now.
Pick: Chargers Moneyline (+245)

















