Betting on quarterback ineptitude is one of my NFL guilty pleasures. I especially like back-breaking interceptions that completely flip the momentum of the game.
That’s why I’m diving headfirst into the quarterback interception market to identify key spots each week to cash in on quarterback miscues.
Here are my two favorite NFL interception props for Week 11.
NFL Interception Props for Week 11
- Patrick Mahomes to Throw an Interception (+105, bet365)
- Justin Herbert to Throw an Interception (+105, FanDuel)
Patrick Mahomes to Throw an Interception (+105)
Chiefs quarterback Patrick Mahomes can sometimes reach the zenith in the NFL when he and his offense are clicking, but even when everything is going right, he can still have a silly throw to lead to an interception.
On Sunday against the Broncos, I expect him to be able to throw successfully. However, I’m betting at least one of those attempts will turn into an interception.
Mahomes only has five interceptions this year, with three of those coming in just the last two games against the Bills and Commanders.
To keep clean and not throw a pick will be a tall order this time because Denver’s defense might be the best in the NFL. The Broncos lead the league in sacks, quarterback hits and total passes defended. The latter is key because they’ve been a bit unlucky on that front: they have 61 passes defended but only five interceptions.
This isn’t sustainable with the Broncos projected to have closer to nine interceptions based on the expected scores. This is the equivalent of your buddy at the bar saying, "He’s DUE!!"
Another reason I locked in Mahomes is that his last couple of trips to Denver have been a bit of a nightmare. He’s only played there twice in the past three seasons, but he had five combined interceptions in those games.
A divisional game, on the road against a strong defense, means this could be a tough outing for the Chiefs' passing game.
Justin Herbert to Throw an Interception (+105)
The Jaguars defense has been a low-key turnover-forcing machine in 2025. They’ve forced 12 interceptions this season while ranking third in INT rate per dropback.
Jacksonville has the second-most passes defended in the NFL (58), and it has forced the opposing quarterback to throw a pick in seven of nine games.
That’s why I’m targeting Chargers QB Justin Herbert to throw an interception.
Herbert has eight interceptions this season, with four of those coming when seeing pressure and four when not.
He’s been an equal-opportunity offender for INT props this season, and the offensive line issues seem to be catching up to him as he has seven turnover-worthy plays this season, with six of those in games where LT Joe Alt was out or left early due to injury.
With the Chargers traveling across the country to a hot and muggy environment, facing a desperate defense that has dropped three of the last four games, I would’ve had this priced closer to -115, so anything at plus-money is good for me.
