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NFL Odds Monday Night Football: Patriots vs. Cardinals Sharp Betting Predictions and Picks

NFL Odds Monday Night Football: Patriots vs. Cardinals Sharp Betting Predictions and Picks article feature image
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Photo by Norm Hall/Getty Images. Pictured: DeAndre Hopkins #10 of the Arizona Cardinals

  • NFL odds for Monday Night Football peg the New England Patriots as road favorites of less than a field goal over the Arizona Cardinals.
  • In addition, the latest NFL odds show the Patriots vs. Cardinals over/under at 43.5 as well.
  • With the help of our NFL predictions and picks we break down the smartest way to bet Patriots vs. Cardinals on Monday Night Football.

Patriots vs. Cardinals Odds

Patriots Odds -2
Cardinals Odds +2
Over/Under 43.5
Date Monday, Dec. 12
Time 8:15 p.m. ET
Channel ESPN

*Odds as of Monday morning

The New England Patriots visit the Arizona Cardinals on Monday Night Football, and live NFL odds suggest that tonight’s game should be very competitive.

The Patriots are between 1.5- and 2-point spread favorites against the Cardinals, so this is a game that can really go either way.

In addition, the latest NFL odds show the Patriots vs. Cardinals over/under at 43.5, which is essentially the consensus line across the market.

So, what is the smartest NFL prediction for Patriots vs. Cardinals on Monday Night Football?

Is there value in the spread? Or should savvy bettors pivot toward tonight’s total?

Using the Action Network’s NFL predictions, here’s how the sharpest NFL bettors are getting down on Monday Night Football.

Patriots vs. Cardinals Prediction

While the move hasn’t been huge, our NFL tools are showing that smart money has quietly taken a position on the Patriots vs. Cardinals under.