Astros vs. Cubs Odds & Betting Predictions - May 24, 2026

Astros at Cubs

6:20 pm • SCHN
8 - 5
Starting Pitchers
pitcherteameraw-l
Shota Imanaga logoS.ImanagaChicago Cubs logo3.916-8
Peter Lambert logoP.LambertHouston Astros logo3.038-5

Astros at Cubs Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Astros
51-54
+1.5
+1.5-158
o7-108
+140
Cubs
58-45
u8
-1.5+136
u7-114
-170
location pinSunday 6:20 p.m.
May 24, 2026
Wrigley FieldChicago
Astros vs. Cubs Expert Picks
Derek Carty
Derek Carty
Last 30d: 26-19-3 (+23.9u)
C.Kelly o0.5 HR+1236
0.25u
There may be some value on Carson Kelly's home runs prop. THE BAT X is projecting him to record 0.11 home runs, and oddsmakers are implying 0.08. The model believes there is a 10% chance he records at least 1 home run, so there is value on the over at +1236. This play is good down to at least +995. Love THE BAT X? Get all of Carty's sports betting projections at EV Analytics https://evanalytics.com/subscribe/mlb?ref=zdlkmgz
Grant Neiffer
Grant Neiffer
Last 30d: 13-87-4 (-8.8u)
C.Walker o0.5 HR+500
1.25u
Frank Ammirante
Frank Ammirante
Last 30d: 335-387-8 (-48.4u)
CHC -1.5+130
0.77u
S.Imanaga u4.5 Hits Allowed-110
1.1u
Under 7.5-123
1u
Adam Kaufman
Adam Kaufman
Last 30d: 121-106-3 (+12.7u)
HOU +146
1.46u
Sean Zerillo
Sean Zerillo
Last 30d: 118-142-10 (-11.0u)
Under 7.5-115
0.58u
Bet to 7 (-115)
CHC -165
0.83u
Bet to -195

Astros vs. Cubs Previews & Analysis

  • Neiffer's 4 Home Run Props for Sunday article feature image

    Neiffer's 4 Home Run Props for Sunday

    Grant Neiffer
    May 24, 2026 UTC
  • Astros vs Cubs: Carty's Prop for Sunday article feature image

    Astros vs Cubs: Carty's Prop for Sunday

    Action Network Staff
    May 24, 2026 UTC
  • The Leadoff: Minion's MLB Breakdown and Bets for Sunday article feature image

    The Leadoff: Minion's MLB Breakdown and Bets for Sunday

    Ryan Minion
    May 24, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Astros vs. Cubs Public Betting Percentages

Away Logo

Astros

Public

24%

Bets%

76%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cubs
45-5820-3225-2629-4116-16
Astros
51-5425-2826-2613-2336-28

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cubs
54-4928-2426-2536-3418-14
Astros
53-46-628-23-225-23-420-15-132-27-5

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cubs
58-4530-2228-2340-3017-15
Astros
51-5426-2725-2716-2033-31

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 23rdHOUL 0-3-1.5 LU 7HOU -149
May 22ndHOUL 2-4-1.5 LU 7HOU -149
May 20thMILL 0-5+1.5 LU 6.5MIL -112
May 19thMILL 2-5+1.5 LU 7.5MIL +103
May 18thMILL 3-9-1.5 LO 10.5MIL -161

Astros vs. Cubs Injury Updates

Astros Injuries

    Cubs Injuries

    • Tyler Austin
      1B

      Austin is out with knee

      Out

    • Justin Steele
      SP

      Steele is out with elbow

      Out

    Astros vs. Cubs Box Score
    Astros Player Stats
    Projected
    PITCHERPCIPKER
    Peter Lambert logoRP.Lambert, P103553
    AJ Blubaugh logoRA.Blubaugh, P29202
    Bryan Abreu logoRB.Abreu, P15100
    Nate Pearson logoRN.Pearson, P20100
    HITTERSH-ABRHRRBI
    Brice Matthews logo1B.Matthews, 2B0-5000
    Brice Matthews logo1B.Matthews, LF0-5000
    Jeremy Pena logo2J.Pena, SS1-4102
    Christian Walker logo3C.Walker, 1B1-4113
    Isaac Paredes logo4I.Paredes, DH2-4000
    Jake Meyers logo5J.Meyers, CF1-4111
    Cam Smith logo6C.Smith, RF1-3200
    Zach Dezenzo logo7Z.Dezenzo, LF0-2100
    Braden Shewmake logo7B.Shewmake, 3B0-0000
    Christian Vazquez logo8C.Vazquez, C0-4000
    Nick Allen logo9N.Allen, 3B3-3212
    Nick Allen logo9N.Allen, 2B3-3212
    Cubs Player Stats
    Projected
    PITCHERPCIPKER
    Shota Imanaga logoLS.Imanaga, P94667
    Ethan Roberts logoRE.Roberts, P16110
    Phil Maton logoRP.Maton, P13100
    Caleb Thielbar logoLC.Thielbar, P13111
    HITTERSH-ABRHRRBI
    Pete Crow-Armstrong logo1P.Crow-Armstrong, CF0-1101
    Nico Hoerner logo2N.Hoerner, SS1-5001
    Michael Busch logo3M.Busch, 1B2-4112
    Alex Bregman logo4A.Bregman, 3B1-4000
    Michael Conforto logo5M.Conforto, LF0-4000
    Seiya Suzuki logo6S.Suzuki, RF0-4000
    Moises Ballesteros logo7M.Ballesteros, DH0-2100
    Carson Kelly logo8C.Kelly, C2-4100
    Kevin Alcantara logo8K.Alcantara, PR0-0000
    Miguel Amaya logo8M.Amaya, C0-0000
    Pedro Ramirez logo9P.Ramirez, 2B1-3101

    Astros vs. Cubs Odds Comparison

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    Astros at Cubs Team Totals

    MatchupOverUnder
    Astros
    51-54
    N/A
    N/A
    Cubs
    58-45
    N/A
    N/A