Astros vs. Cubs Odds & Betting Predictions - May 24, 2026
Astros at Cubs
6:20 pm • SCHNStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 3.91 | 6-8 | ||
![]() | 3.03 | 8-5 |
Astros at Cubs Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Astros 51-54 | +1.5 | +1.5-158 | o7-108 | +140 |
Cubs 58-45 | u8 | -1.5+136 | u7-114 | -170 |

Wrigley FieldChicago
Astros vs. Cubs Expert Picks
Derek Carty
Last 30d: 26-19-3 (+23.9u)
C.Kelly o0.5 HR+1236
0.25u
There may be some value on Carson Kelly's home runs prop. THE BAT X is projecting him to record 0.11 home runs, and oddsmakers are implying 0.08. The model believes there is a 10% chance he records at least 1 home run, so there is value on the over at +1236. This play is good down to at least +995.
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Grant Neiffer
Last 30d: 13-87-4 (-8.8u)
C.Walker o0.5 HR+500
1.25u
Frank Ammirante
Last 30d: 335-387-8 (-48.4u)
CHC -1.5+130
0.77u
S.Imanaga u4.5 Hits Allowed-110
1.1u
Under 7.5-123
1u
Adam Kaufman
Last 30d: 121-106-3 (+12.7u)
HOU +146
1.46u

Sean Zerillo
Last 30d: 118-142-10 (-11.0u)
Under 7.5-115
0.58u
Bet to 7 (-115)
CHC -165
0.83u
Bet to -195
Astros vs. Cubs Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Astros vs. Cubs Public Betting Percentages
Betting Trends
- Cubs are 3-2 in their last 5 games.
- Cubs are 2-3 in their last 5 games against the spread
- Cubs are 25-26 in their road games against the spread
- The totals have gone OVER in 3 of Cubs' last 5 games
- The totals have gone OVER in 28 of Cubs' 52 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Astros vs. Cubs Injury Updates

Astros Injuries

Cubs Injuries
- Tyler Austin1B
Austin is out with knee
Out
- Justin SteeleSP
Steele is out with elbow
Out
Astros vs. Cubs Box Score
Astros Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 103 | 5 | 5 | 3 | |
![]() | 29 | 2 | 0 | 2 | |
![]() | 15 | 1 | 0 | 0 | |
![]() | 20 | 1 | 0 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 0-5 | 0 | 0 | 0 |
![]() | 0-5 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 2 |
![]() | 1-4 | 1 | 1 | 3 |
![]() | 2-4 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 1 | 1 |
![]() | 1-3 | 2 | 0 | 0 |
![]() | 0-2 | 1 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 3-3 | 2 | 1 | 2 |
![]() | 3-3 | 2 | 1 | 2 |
Cubs Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 94 | 6 | 6 | 7 | |
![]() | 16 | 1 | 1 | 0 | |
![]() | 13 | 1 | 0 | 0 | |
![]() | 13 | 1 | 1 | 1 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 0-1 | 1 | 0 | 1 |
![]() | 1-5 | 0 | 0 | 1 |
![]() | 2-4 | 1 | 1 | 2 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-2 | 1 | 0 | 0 |
![]() | 2-4 | 1 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 1-3 | 1 | 0 | 1 |
Astros vs. Cubs Odds Comparison
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Astros at Cubs Team Totals
MatchupOverUnder | ||
|---|---|---|
Astros 51-54 | N/A | N/A |
Cubs 58-45 | N/A | N/A |
































