Diamondbacks vs Dodgers Predictions, Parlay, Picks, Odds for Wednesday, May 21

Diamondbacks vs Dodgers Predictions, Parlay, Picks, Odds for Wednesday, May 21 article feature image
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Credit: Imagn Images. Pictured: Los Angeles Dodgers DH Shohei Ohtani.

The Los Angeles Dodgers host the Arizona Diamondbacks on May 21, 2025. First pitch from Dodger Stadium is scheduled for 10:10 p.m. EDT; the game will be broadcast on SportsNet LA.

Read my Diamondbacks vs Dodgers prediction and same-game parlay picks below.

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My Diamondbacks vs Dodgers Predictions, Parlay

  • Dodgers ML
  • Shohei Ohtani Over 1.5 Total Bases

Parlay Odds: +165 (BetMGM)


Diamondbacks vs Dodgers Odds

Diamondbacks Logo
May 21, 2025
10:10 p.m. EDT
SportsNet LA
Dodgers Logo
Diamondbacks Odds
SpreadTotalMoneyline
+1.5
-165
9
-120 / -100
+120
Dodgers Odds
SpreadTotalMoneyline
-1.5
+140
9
-120 / -100
-145
Odds via BetMGM. Get up-to-the-minute MLB odds here.
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Diamondbacks vs Dodgers Preview, Parlay Picks

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Dodgers ML

The Dodgers snapped a four-game losing streak with a 4-3 walk-off win on Tuesday.

I'm banking on Dave Roberts' squad carrying the momentum into Wednesday.

The Diamondbacks will start their Ace, Corbin Burnes, for this matchup. But no matter, the Dodgers' elite lineup has plenty of experience against Burnes and should use that to their advantage.

Conversely, Dodgers starting pitcher Dusty May has held this current Snakes' lineup to a .219 batting average in 69 career at-bats.


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Shohei Ohtani Over 1.5 Total Bases

The former MVP draws another favorable matchup on Wednesday.

Shohei Ohtani has produced four hits in eight lifetime at-bats against Burnes, suitable for a .500 average.

I expect Ohtani will continue this success against Burnes on Wednesday and cash this total bases prop.


Diamondbacks vs Dodgers Parlay

  • Dodgers ML
  • Shohei Ohtani Over 1.5 Total Bases

Parlay Odds: +165 (BetMGM)


Diamondbacks vs Dodgers Betting Trends


Diamondbacks vs Dodgers Weather


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About the Author
Matt is a Senior Betting Analyst at Action Network. He has been in the betting industry for eight years and has worked as a Lead Betting Analyst for numerous companies over the years. Matt specializes in multiple sports, including NFL, NBA, MLB, NHL, NCAAF, NCAAB, UFC, Golf and NASCAR.

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