Astros vs. Red Sox MLB Odds, Picks: Run Line Prediction Using Historical Data (Wednesday, May 18)

Houston Astros vs. Boston Red Sox Odds

*Odds are current as of Wednesday afternoon

This contest on Wednesday night fits a historically-profitable Action Network betting system that reports a return on investment (ROI) of 8%.

If you had bet $100 on each game that has fit the betting trend, you'd be up over $8,500 since 2005 — that's about $525 per year.

For reference, the annual average return of the S&P 500 — roughly the value of the American stock market — has been 8% for about a century. Since the start of the New Year, that index is down roughly 17%.

Bitcoin, for instance, is down about 39% since the New Year.

This betting system also has a win rate of about 59%. For reference, a win rate of 52.5% is enough to turn a profit.

Wednesday's MLB betting system involves contrarian betting — finding value by going against the public's prevailing notions — and targets the run line.

MLB Betting System Picks for Wednesday