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Orioles vs Pirates Prediction, Pick, MLB Odds for Saturday, April 4

Orioles vs Pirates Prediction, Pick, MLB Odds for Saturday, April 4 article feature image
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Brad Penner-Imagn Images. Pictured: Pirates SP Carmen Mlodzinski

The Pittsburgh Pirates host the Baltimore Orioles on April 4, 2026. First pitch from PNC Park is scheduled for 4:05 p.m. ET. The game will be broadcast on MASN.

The Orioles are favored by -110 on the moneyline and by -1.5 on the run line. The Pirates are -106 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find our MLB picks and Orioles vs Pirates prediction below, as well as probable pitchers, weather report, and more.


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Orioles vs Pirates Prediction

  • Orioles vs Pirates Pick: Carmen Mlodzinski Over 4.5 Strikeouts (-112)

Our Orioles vs Pirates best bet is on Carmen Mlodzinski to record over 4.5 strikeouts today. Make sure to find the best odds by checking our live MLB odds page.


Orioles vs Pirates Odds

Orioles Logo
Saturday, April 4
4:05 p.m. ET
MASN
Pirates Logo
Orioles Odds
SpreadTotalMoneyline
-1.5
+150
8.5
-108o / -112u
-110
Pirates Odds
SpreadTotalMoneyline
+1.5
-182
8.5
-108o / -112u
-106
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Orioles vs Pirates spread: Orioles -1.5 (+150), Pirates +1.5 (-182)
  • Orioles vs Pirates over/under: 8.5 (-108o / -112u)
  • Orioles vs Pirates moneyline: Orioles -110, Pirates -106


Orioles vs Pirates Projected Starting Pitchers

RHP Shane Baz (BAL)StatRHP Carmen Mlodzinski (PIT)
0-0W-L0-0
0.2fWAR (FanGraphs)0.3
6.75 / 3.47ERA / xERA4.15 / 2.07
2.25 / 4.46FIP / xFIP-0.51 / 0.51
1.31WHIP1.38
19.0K-BB%40.0
25.0GB%50.0
107Stuff+92
93Location+121

Orioles vs Pirates Preview

Action PRO projects Pirates starter Carmen Mlodzinski for 6.1 strikeouts in their matchup against the Orioles tonight, giving us a solid 18% edge against the market when compared to his current prop line of over/under 4.5, which is good enough to tag the Over with an A grade in our system.

He already fanned eight batters in his first outing of the season, in just 4 and 1/3 innings against the Mets.

That was against a lineup that does not strike out that much, ranking eighth so far this season in K%.

Today, Mlodzinski will go against a Baltimore lineup that has the 11th-highest strikeout percentage in the majors this season, with 25.5%.

Let's back him tonight to go over his Ks line against the Orioles.

Pick: Carmen Mlodzinski Over 4.5 Strikeouts (-122, FanDuel)

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Orioles vs Pirates Weather


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