Orioles vs Mariners Prediction, Pick, Odds for Thursday, June 5

Orioles vs Mariners Prediction, Pick, Odds for Thursday, June 5 article feature image
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Credit: Imagn Images. Pictured: Seattle Mariners SP Bryan Woo.

The Seattle Mariners host the Baltimore Orioles on June 5, 2025. First pitch from T-Mobile Park is scheduled for 3:40 p.m. EDT; the game will be broadcast on MASN2.

Read our Orioles vs Mariners prediction and MLB pick below.

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My Orioles vs Mariners Prediction

  • Orioles vs Mariners Picks: F5 Under 4 (-125, BetMGM)

My Orioles vs Mariners best bet is on the first-half Under. Make sure to find the best odds by checking our live MLB odds page.


Orioles vs Mariners Odds

Orioles Logo
June 5, 2025
3:40 p.m. EDT
MASN2
Mariners Logo
Orioles Odds
SpreadTotalMoneyline
+1.5
-180
7.5
-105o / -115u
+125
Mariners Odds
SpreadTotalMoneyline
-1.5
+145
7.5
-105o / -115u
-150
Odds via BetMGM. Get up-to-the-minute MLB odds here.
BetMGM Logo

Charlie Wright’s Orioles vs Mariners Preview

It seemed like Seattle had solved T-Mobile Park early in the season.

The Mariners were rolling on offense at home in what had been the worst place to hit in the league.

But that's all over now.

The Mariners rank dead last among MLB lineups in OPS and wOBA vs. RHP at home over the past 30 days. They're only slightly better overall in that span (29th in both metrics). Seattle ranks 25th in wRC+ against righties since the start of May.

Meanwhile, Baltimore has struggled on offense for much of the season.

The O’s rank 19th in OPS and 20th in wOBA vs. RHP over the past 30 days.

They’ll square off against Bryan Woo, who has been one of the most consistent starters in the league. Woo posted a crisp 2.58 ERA in May, including four straight quality starts. He's one off the league lead in that category.

Lefties have plagued Woo at times, but he's held them to a .231/.264/.410 slash line this season.

Zach Eflin will oppose Woo.

He had pitched well through 3 starts before hitting the IL with a lat strain. Eflin struggled in three outings since returning, but dominated the White Sox last time out with seven scoreless innings.

It was good to see Eflin's velocity slightly up in that start. He gets another favorable matchup here.

Pick: F5 Under 4 (-125, BetMGM)


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