The Cleveland Guardians host the Cincinnati Reds on May 15, 2026. First pitch from Progressive Field is scheduled for 7:10 p.m. EDT. The game will be broadcast on CINR.
The Guardians are favored by -134 on the moneyline and by -1.5 on the run line. The Reds are +114 on the moneyline and +1.5 on the run line. The total is set at 8 runs.
Find my MLB picks and Reds vs Guardians prediction below, as well as probable pitchers, weather report, and more.
Reds vs Guardians Prediction
- Reds vs Guardians Pick: Andrew Abbott Under 4.5 Strikeouts (-138)
My Reds vs Guardians best bet is on Andrew Abbott to record under his strikeouts prop. Make sure to find the best odds by checking our live MLB odds page.
Reds vs Guardians Odds
| Reds Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -200 | 8 -110o / -110u | +114 |
| Guardians Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +162 | 8 -110o / -110u | -134 |
- Reds vs Guardians moneyline: Reds +114, Guardians -134
- Reds vs Guardians over/under: 8 (-110o / -110u)
- Reds vs Guardians spread: Guardians -1.5 (+162), Reds +1.5 (-200)
Reds vs Guardians Probable Pitchers
| LHP Andrew Abbott (CIN) | Stat | RHP Tanner Bibee (CLE) |
|---|---|---|
| 2-2 | W-L | 0-5 |
| 0.6 | fWAR (FanGraphs) | 0.5 |
| 4.47/4.73 | ERA / xERA | 4.17/3.79 |
| 4.38/4.62 | FIP / xFIP | 4.39/3.90 |
| 6.4% | K-BB% | 13.9% |
| 43.2% | GB% | 41.9% |
| .310 | BABIP | .293 |
| 93 | Stuff+ | 104 |
| 98 | Location+ | 97 |
Reds vs Guardians MLB Betting Preview
Tough spot here for strikeouts for Andrew Abbott against this pesky Guardians team, and with this one already sitting as high as -150 on some other books, we are getting a decent price at -138.
Abbott is averaging just 0.71 strikeouts per inning this season, and his season high is 5 strikeouts.
He has a minuscule 12% strikeout rate against righties, and he'll likely see six of those from the Guardians.
His 31.1% K rate against lefties has certainly been impressive, but the problem for him is the three lefties projected to start for the Guardians all have strikeout rates under 17% against LHP since the start of last season, with two of them (Steven Kwan and Chase DeLauter) under 11% in a sizable sample.
As a team, the Guardians have the 5th-lowest strikeout rate against LHP this season at just 18.9%, making this number too high and an under I will be attacking.
Pick: Andrew Abbott Under 4.5 Strikeouts (-138)
