The Pittsburgh Pirates host the Cincinnati Reds on May 19, 2025. First pitch from PNC Park is scheduled for 6:40 p.m. EDT; the game will be broadcast on Fox Sports 1.
Read our Reds vs Pirates predictions and same-game parlay picks below.
My Reds vs Pirates Predictions, Parlay
- Mitch Keller Over 5.5 Strikeouts
- Cincinnati Reds ML
Parlay Odds: +185 (Fanatics)
Reds vs Pirates Odds
| Reds Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +145 | 8 -110o / -110u | -118 |
| Pirates Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -180 | 8 -110o / -110u | -102 |
Reds vs Pirates Projected Starting Pitchers
| LHP Nick Lodolo (CIN) | Stat | RHP Mitch Keller (PIT) |
|---|---|---|
| 3-4 | W-L | 1-5 |
| 0.9 | fWAR (FanGraphs) | 1.0 |
| 3.42 / 4.08 | ERA /xERA | 4.15 / 4.76 |
| 3.83 / 4.05 | FIP / xFIP | 3.59 / 4.23 |
| 1.08 | WHIP | 1.33 |
| 14.9% | K-BB% | 11.9% |
| 42.5% | GB% | 38.9% |
| 101 | Stuff+ | 97 |
| 100 | Location+ | 99 |
Reds vs Pirates Preview, Parlay Picks
Mitch Keller Over 5.5 Strikeouts
The struggling Pirates will face the Reds in a divisional matchup.
I'm taking this slight negative correlation parlay: Mitch Keller will go over his strikeouts, and Cincinnati will win.
This season, Keller has struggled quite a bit, with a 1-5 record behind a 4.15 ERA.
That said, though, he’s eclipsed 5.5 strikeouts in three out of his past four outings.
Also, the Reds strike out at a top-five rate among MLB lineups (24%).
Cincinnati Reds ML
With all that said, I'm still betting that the Reds will win.
They are on a four-game winning streak after sweeping the always-annoying Cleveland Guardians.
Expect them to continue their winning ways against a Pirates team that is going in the complete opposite direction.
Reds vs Pirates Parlay
- Mitch Keller Over 5.5 Strikeouts
- Cincinnati Reds ML
Parlay Odds: +185 (Fanatics)
Reds vs Pirates Betting Trends
