The St. Louis Cardinals host the Cincinnati Reds on September 17, 2025. First pitch from Busch Stadium is scheduled for 1:15 p.m. EDT; the game will be broadcast on FDSMW.
Find my MLB betting preview and Reds vs Cardinals prediction below, as well as probable pitchers, betting trends, injury reports and more.
My Reds vs Cardinals Prediction
- Reds vs Cardinals picks: Under 8.5
My Reds vs Cardinals best bet is Under 8.5 with the best odds currently on Bet365. Make sure to find the best odds by checking our live MLB odds page.
Reds vs Cardinals Odds
| Reds Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +141 | 8.5 -109o / -111u | -118 |
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -172 | 8.5 -109o / -111u | -101 |
Reds vs Cardinals Projected Starting Pitchers
| RHP Brady Singer (CIN) | Stat | RHP Andre Pallante (STL) |
|---|---|---|
| 13-10 | W-L | 6-14 |
| 2.8 | fWAR (FanGraphs) | 0.7 |
| 3.94 / 4.15 | ERA /xERA | 5.34 / 4.35 |
| 3.88 / 4.23 | FIP / xFIP | 4.69 / 4.13 |
| 1.24 | WHIP | 1.43 |
| 14.1% | K-BB% | 6.9% |
| 39.4% | GB% | 60.2% |
| 95 | Stuff+ | 94 |
| 101 | Location+ | 102 |
Reds vs Cardinals Prediction, Betting Analysis
This system bets the under in daytime games where solid visiting arms suppress scoring and the home offense is steady but not explosive: Day games (11:00–14:59 ET) often play slower due to sun, shadows, and shorter rest.
Visitor SP filters (ERA 3–4.76 and WHIP 1.07–1.39) identify efficient pitchers capable of limiting damage without elite notoriety.
Home team hit rate between 7.81 and 8.24 ensures average offensive output—enough to avoid “over” volatility but not dominate.
The regular season only avoids erratic postseason scoring.
Combined with lower totals and calm game tempos, this approach isolates a pocket where public expectations may overshoot actual output.
Pick: Under 8.5
