Guardians vs Tigers Predictions, Parlay, Picks, Odds for Saturday, May 24

Guardians vs Tigers Predictions, Parlay, Picks, Odds for Saturday, May 24 article feature image
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Pictured: Spencer Torkelson. (Credit: Lon Horwedel-Imagn Images)

The Detroit Tigers host the Cleveland Guardians on May 24, 2025. First pitch from Comerica Park is scheduled for 7:15 p.m. ET; the game will be broadcast on FOX.

Find my MLB betting preview and Guardians vs Tigers prediction below, as well as probable pitchers, betting trends, injury reports and more.

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My Guardians vs Tigers Predictions, Parlay

  • Tigers ML
  • Spencer Torkelson 2+ Bases

Parlay odds: +260 (DraftKings)


Guardians vs Tigers Odds

Guardians Logo
Saturday, May 24
7:15 p.m. ET
FOX
Tigers Logo
Guardians Odds
SpreadTotalMoneyline
+1.5
-185
8
-115o / -105u
+125
Tigers Odds
SpreadTotalMoneyline
-1.5
+150
8
-115o / -105u
-150
Odds via BetMGM. Get up-to-the-minute MLB odds here.
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Guardians vs Tigers Projected Starting Pitchers

RHP Luis Ortiz (CLE)StatRHP Casey Mize (DET)
2-5W-L6-1
0.5fWAR (FanGraphs)0.7
4.66/5.11ERA /xERA2.53/2.67
4.07/3.65FIP / xFIP3.90/3.83
1.39WHIP1.01
15.6K-BB%15.6
44.7GB%43.9
97Stuff+99
95Location+102

Guardians vs Tigers Preview, Parlay Picks

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Tigers ML

The Tigers are poised to bounce back after back-to-back losses to open the series.

Right-hander Casey Mize is expected to start on Saturday for Detroit. He hasn’t pitched since May 8, but he’s been outstanding this season, boasting a 2.53 ERA and a 6-1 record.

Meanwhile, Guardians starter Luis Ortiz has struggled on the road, posting a 6.58 ERA over 26.0 innings pitched.


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Spencer Torkelson 2+ Bases

Spencer Torkelson is a long-ball threat every time he steps to the plate.

The Tigers' first baseman has racked up 26 extra-base hits this season.

He’s also had success against Ortiz, batting .500 in four career at-bats.


Guardians vs Tigers Parlay

  • Tigers ML
  • Spencer Torkelson 2+ Bases

Parlay odds: +260 (DraftKings)


Guardians vs Tigers Betting Trends



Guardians vs Tigers Weather


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About the Author
Matt is a Senior Betting Analyst at Action Network. He has been in the betting industry for eight years and has worked as a Lead Betting Analyst for numerous companies over the years. Matt specializes in multiple sports, including NFL, NBA, MLB, NHL, NCAAF, NCAAB, UFC, Golf and NASCAR.

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