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Rockies vs Padres Prediction, Pick, Odds for Friday, September 12

Rockies vs Padres Prediction, Pick, Odds for Friday, September 12 article feature image
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Pictured: JP Sears. (Credit: Denis Poroy-Imagn Images)

The San Diego Padres host the Colorado Rockies on September 12, 2025. First pitch from PETCO Park is scheduled for 9:40 p.m. EDT; the game will be broadcast on COLR.

Find my MLB betting preview and Rockies vs Padres prediction below, as well as probable pitchers, betting trends, injury reports and more.

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My Rockies vs Padres Prediction

  • Rockies vs Padres pick: Under 8.5

My Rockies vs Padres best bet is on the under total runs. Make sure to find the best odds by checking our live MLB odds page.


Rockies vs Padres Odds

Rockies Logo
Friday, Sep 12
9:40 p.m. ET
COLR
Padres Logo
Rockies Odds
SpreadTotalMoneyline
+1.5
+105
8.5
-105o / -115u
+210
Padres Odds
SpreadTotalMoneyline
-1.5
-125
8.5
-105o / -115u
-260
Odds via Fanatics. Get up-to-the-minute MLB odds here.
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Rockies vs Padres Projected Starting Pitchers

RHP Tanner Gordon (COL)StatLHP JP Sears (SDP)
5-6W-L8-10
0.7fWAR (FanGraphs)0.5
6.60/5.83ERA /xERA5.01/4.22
4.63/4.45FIP / xFIP5.17/4.85
1.60WHIP1.30
11.4%K-BB%13.6%
34.8%GB%28.7%
83Stuff+95
105Location+106

Rockies vs Padres Prediction, Betting Analysis

The San Diego Padres are heavy -260 favorites to take Game 2 of their four-game set against the Colorado Rockies, who sit at +210 on the moneyline. Oddsmakers have set the over/under at 8.5 runs.

San Diego opened the series with a 2-0 win on Thursday night behind Jackson Merrill’s homer and Randy Vasquez’s career-best nine strikeouts across six innings. The shutout loss marked another tough offensive showing for Colorado, which continues to rank near the bottom of MLB in scoring.

On the mound Friday, the Rockies hand the ball to Tanner Gordon, while the Padres counter with left-hander JP Sears. Neither arm is elite, but this setup fits squarely into the Series Unders: Off Low-Scoring Games system from Evan Abrams.

This angle targets spots where teams enter the second or later game of a series following minimal offense in the opener. The idea is that the market often overcorrects, but offensive stagnation tends to linger, especially in early or mid-series matchups.

MLB Icon
Evan Abrams / Bet Labs – Series Unders: Off Low-Scoring Games
betting on the Under
the series game # is between 2 and 10
the Home teams' 1 Game points scored streak is between 0 and 2
the Visiting teams' 1 Game points scored streak is between 0 and 2
the game is played during the Regular season
$18.366
WON
1405-1131-121
RECORD
55%
WIN%

Pick: Under 8.5 (-115, Fanatics)


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