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Rockies vs Padres Prediction, Pick, MLB Odds for Friday, April 10

Rockies vs Padres Prediction, Pick, MLB Odds for Friday, April 10 article feature image
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Denis Poroy-Imagn Images. Pictured: Padres 3B Manny Machado

The San Diego Padres host the Colorado Rockies on April 10, 2026. First pitch from Petco Park is scheduled for 9:40 p.m. ET. The game will be broadcast on COLR.

The Padres are favored by -186 on the moneyline and by -1.5 on the run line. The Rockies are +153 on the moneyline and +1.5 on the run line. The total is set at 8 runs.

Find my MLB picks and Rockies vs Padres prediction below, as well as probable pitchers, weather report, and more.


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Rockies vs Padres Prediction

  • Rockies vs Padres Pick: Manny Machado 1+ Singles (+113)

My Rockies vs Padres best bet is Manny Machado to hit one or more singles in this game. Make sure to find the best odds by checking our live MLB odds page.


Rockies vs Padres Odds

Rockies Logo
Friday, Apr 10
9:40 p.m. ET
COLR
Padres Logo
Rockies Odds
SpreadTotalMoneyline
+1.5
-136
8
-115o / -105u
+153
Padres Odds
SpreadTotalMoneyline
-1.5
+113
8
-115o / -105u
-186
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo
  • Rockies vs Padres spread: Rockies +1.5 (-136), Padres -1.5 (+113)
  • Rockies vs Padres over/under: 8 (-115o / -105u)
  • Rockies vs Padres moneyline: Rockies +153, Padres -186


Rockies vs Padres Projected Starting Pitchers

RHP Tomoyuki Sugano (COL)StatRHP Walker Buehler (SD)
1-0W-L0-1
0.1fWAR (FanGraphs)-0.1
1.69 / 3.74ERA / xERA9.45 / 4.88
4.74 / 3.60FIP / xFIP5.70 / 4.50
0.84WHIP1.95
14.6K-BB%6.1
51.7GB%65.0
78Stuff+90
114Location+79

Rockies vs Padres Preview

For tonight’s matchup between San Diego and Colorado at Petco Park, targeting Manny Machado to record at least one single is a high-value play.

Action PRO projects the Padres star third baseman for 0.83 singles, giving us a solid 9.4% edge against the market when compared to his current prop line of over/under 0.5, which is good enough to tag the Over with a B- grade in our system.

Machado will face Rockies starter Tomoyuki Sugano, who had a terrible second half last season with the Orioles and is now looking for a fresh start in Colorado, of all places.

Sugano has done well in his first two starts, but right-handed hitters have done much better against him than lefties. Plus, the Japanese is more of a control pitcher who does not miss too many bats, so Machado will be able to use the ample spaces of Petco to get a single off him tonight.


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Rockies vs Padres Picks

Machado has been one of the few bright spots for the Padres offense in this terrible 2026 start of the season, and this is bound to change very soon.

He's hit at least a single in three of his past four games.

Also, has been a menace against the Rockies’ staff recently. Over his last five games against Colorado, he is batting .389 (7-for-18), with six runs scored and three home runs.

If he doesn't get a single off Sugano, he will have chances against the Rockies relievers.

Even though the Colorado bullpen ranks ninth this season in ERA with a splendid 2.98, it doesn't seem sustainable given the quality of their pitchers.

Pick: Manny Machado 1+ Singles (+113, DraftKings)

Playbook

Rockies vs Padres Weather


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