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Tigers vs Red Sox Predictions, Parlay, Picks, Odds for Friday, September 26

Tigers vs Red Sox Predictions, Parlay, Picks, Odds for Friday, September 26 article feature image
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Pictured: Casey Mize. (Credit: Junfu Han / USA TODAY NETWORK via Imagn Images)

The Detroit Tigers (86-73) head to Beantown to face the Boston Red Sox (87-72) on September 26, 2025. First pitch from Fenway Park is scheduled for 7:10 p.m. EDT; the game will be broadcast on Apple TV+.

Find my MLB betting pick and Tigers vs Red Sox prediction below, as well as probable pitchers, odds, betting trends, injury reports and more.

Playbook

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My Tigers vs Red Sox Predictions, Parlay

  • Tigers ML
  • Jarren Duran 1+ Hit

Parlay odds: +170 (bet365)


Tigers vs Red Sox MLB Odds

Tigers Logo
Friday, Sep 26
7:10 p.m. ET
Apple TV+
Red Sox Logo
Tigers Odds
SpreadTotalMoneyline
+1.5
-200
8.5
-120o / 100u
+100
Red Sox Odds
SpreadTotalMoneyline
-1.5
+170
8.5
-120o / 100u
-120
Odds via bet365. Get up-to-the-minute MLB odds here.
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Tigers vs Red Sox Projected Starting Pitchers

RHP Casey Mize (DET)StatLHP Kyle Harrison (BOS)
14-6W-L1-1
2.0fWAR (FanGraphs)0.4
3.91/3.77ERA /xERA3.58/3.89
4.04/4.04FIP / xFIP3.88/3.98
1.28WHIP1.19
15.8%K-BB%15.3%
38.8%GB%38.5%
96Stuff+97
106Location+114

Tigers vs Red Sox Preview, Parlay Picks

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Tigers ML

We will trust the struggling road team tonight.

Both teams enter this series desperate for a playoff berth.

Detroit has been part of one of the biggest collapses in MLB history. The Tigers held a 12.5-game lead in the AL Central earlier this month and now enter the season's final series tied with the Guardians for first place in the division.

However, Cleveland holds the tiebreaker, meaning Detroit does not control its own destiny.

Casey Mize is the stronger arm in this matchup. Mize has posted a 3.91 ERA this season and has allowed three runs or fewer in four consecutive starts.

I expect the Tigers' offense to perform well against southpaw Kyle Harrison.


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Jarren Duran 1+ Hit

The Red Sox left fielder ranks second on the team with 157 hits this season.

Duran draws a favorable matchup tonight. The 29-year-old is 3-for-8 in his career against Mize (.375).

He is expected to continue his success tonight.


Tigers vs Red Sox Parlay Picks

  • Tigers ML
  • Jarren Duran 1+ Hit

Parlay odds: +170 (bet365)


Tigers vs Red Sox Betting Trends


Tigers vs Red Sox Weather


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