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Astros vs White Sox Prediction, Pick, MLB Odds for Friday, July 24

Astros vs White Sox Prediction, Pick, MLB Odds for Friday, July 24 article feature image
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Jul 22, 2026; Houston, Texas, USA; Houston Astros pitcher Enyel de Los Santos (65) reacts after getting a strikeout during the seventh inning against the Miami Marlins at Daikin Park. Mandatory Credit: Troy Taormina-Imagn Images

The Chicago White Sox host the Houston Astros on July 24, 2026. First pitch from Rate Field is scheduled for 7:40 p.m. EDT. The game will be broadcast on SCHN.

The White Sox are favored by -134 on the moneyline and by -1.5 on the run line. The Astros are +114 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find my MLB picks and Astros vs White Sox prediction below, as well as probable pitchers, weather report, and more.


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Astros vs White Sox Prediction

  • Astros vs White Sox Pick: Astros ML (+115 or Better)

My Astros vs White Sox best bet is on Houston. Make sure to find the best odds by checking our live MLB odds page.


Astros vs White Sox Odds

Astros Logo
Friday, Jul 24
7:40 p.m. ET
SCHN
White Sox Logo
Astros Odds
SpreadTotalMoneyline
+1.5
-182
8.5
-122o / -100u
+114
White Sox Odds
SpreadTotalMoneyline
-1.5
+150
8.5
-122o / -100u
-134
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Astros vs White Sox moneyline: Astros +114, White Sox -134
  • Astros vs White Sox over/under: 8.5 (-122 / -100)
  • Astros vs White Sox spread: White Sox -1.5 (+150), Astros +1.5 (-182)

Astros vs White Sox Probable Pitchers

RHP Spencer Arrighetti (HOU)StatRHP Davis Martin (CHW)
7-5W-L9-5
0.5fWAR (FanGraphs)3.0
4.34 / 5.06ERA / xERA3.31 / 4.32
4.97 / 4.88FIP / xFIP3.06 / 3.76
10.3%K-BB%14.5%
36.4%GB%42.7%
.248BABIP.320
99Stuff+90
90Location+95

Astros vs White Sox MLB Betting Preview

Our own Sean Zerillo projects some value on Houston in this game.

If you want to dive deeper into this matchup, I highly recommend checking out BARTOLO, our new PRO baseball betting tool giving all our PRO subscribers access to the data he uses to project games each day.

Opening Pitch: How To Bet Friday's Slate Using BARTOLO Image

Some of the things you get with BARTOLO include his full game projection:

Breakdowns of the starting pitchers:

Breakdowns of the bullpens:

And breakdowns of the lineups, where Houston has the largest advantage in this game:

Get a PRO subscription today to get access to all of these tools and much more.

Pick: Astros ML (+115 or Better)


Astros vs White Sox Weather


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