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Astros vs Angels Prediction, Pick, MLB Odds for Wednesday, July 29

Astros vs Angels Prediction, Pick, MLB Odds for Wednesday, July 29 article feature image
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Jul 28, 2026; Anaheim, California, USA; Houston Astros catcher Christian Vazquez (2) hits a single against the Los Angeles Angels during the ninth inning at Angel Stadium. Mandatory Credit: Gary A. Vasquez-Imagn Images

The Los Angeles Angels host the Houston Astros on July 29, 2026. First pitch from Angel Stadium is scheduled for 9:38 p.m. EDT. The game will be broadcast on ABTV.

The Astros are favored by -136 on the moneyline and by -1.5 on the run line. The Angels are +116 on the moneyline and +1.5 on the run line. The total is set at 9.5 runs.

Find my MLB picks and Astros vs Angels prediction below, as well as probable pitchers, weather report, and more.


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Astros vs Angels Prediction

  • Astros vs Angels Pick: Over 10 (+100 or Better)

My Astros vs Angels best bet is on the Over. Make sure to find the best odds by checking our live MLB odds page.


Astros vs Angels Odds

Astros Logo
Wednesday, Jul 29
9:38 p.m. ET
ABTV
Angels Logo
Astros Odds
SpreadTotalMoneyline
-1.5
+118
9.5
-115o / -105u
-136
Angels Odds
SpreadTotalMoneyline
+1.5
-142
9.5
-115o / -105u
+116
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Astros vs Angels moneyline: Astros -136, Angels +116
  • Astros vs Angels over/under: 9.5 (-115 / -105)
  • Astros vs Angels spread: Astros -1.5 (+118), Angels +1.5 (-142)

Astros vs Angels Kalshi MLB Odds

Astros vs Angels Polymarket MLB Odds


Astros vs Angels MLB Betting Preview

Our own Sean Zerillo projects some value on the Over in this matchup.

If you'd like to learn more about this projection, I recommend checking out BARTOLO, our new PRO baseball betting tool that gives our PRO subscribers access to all the data we use to project games each day.

Get The Edge: Wednesday's Sharpest Bets Shown by BARTOLO Image

Pick: Over 10 (+100 or Better)


Astros vs Angels Weather


Get the latest coverage on MLB Weather.
Author Profile
About the Author

Tanner McGrath covers college basketball, college football and Major League Baseball at Action Network. He is a contributor to Payoff Pitch, Action Network’s Major League Baseball betting podcast. He's been working in the space for more than five years with past journalism experience in Canadian collegiate sports, finance and economics. He has an obsession with America East basketball, betting the Miami Marlins and sweating out home underdogs.

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